⁶⁸Ga-PSMA Uptake in Pulmonary Tuberculosis: A Pitfall in Prostate Cancer PET Imaging

Introduction

⁶⁸Ga-PSMA ligand PET/CT is a novel imaging modality for prostate cancer. Nevertheless, PSMA expression has been detected in various solid tumors including lung adenocarcinoma. It is not rare for prostate cancer to metastasize to the lung, and it is difficult to differentiate primary lung lesions from metastatic prostate cancer to the lung, especially when there is a focal PSMA uptake in the lung lesion [1]. Here we report a case of prostate cancer with intensive PSMA expression in pulmonary tuberculosis.

Publikationsverlauf

Artikel online veröffentlicht:
10. Dezember 2020

• References

• 1 Usmani S, Sadeq A, Marafi F. et al. ⁶⁸Ga-PMSA Uptake in the Lung: Metastatic Versus Primary Lung Tumor. Clinical nuclear medicine 2020; 45: e80-e82
• 2 Sheikhbahaei S, Afshar-Oromieh A, Eiber M. et al. Pearls and pitfalls in clinical interpretation of prostate-specific membrane antigen (PSMA)-targeted PET imaging. European journal of nuclear medicine and molecular imaging 2017; 44: 2117-2136
• 3 Pyka T, Weirich G, Einspieler I. et al. ⁶⁸Ga-PSMA-HBED-CC PET for Differential Diagnosis of Suggestive Lung Lesions in Patients with Prostate Cancer. J Nucl Med 2016; 57: 367-371
• 4 Damjanovic J, Janssen JC, Furth C. et al. (68)Ga-PSMA-PET/CT for the evaluation of pulmonary metastases and opacities in patients with prostate cancer. Cancer Imaging 2018; 18: 20
• 5 Liepe K, Baehr M, Kuhn B. False-positive findings in inflammatory processes using 99mTc-PSMA. Nuklearmedizin 2020;