Open Access
CC BY-NC-ND 4.0 · Endosc Int Open 2021; 09(03): E331-E337
DOI: 10.1055/a-1333-1108
Original article

Comparison of colonoscopy after colonic diverticulitis and positive fecal immunochemical tests for the detection of colorectal neoplasia

Dai Nakamatsu
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Tsutomu Nishida
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Shinji Kuriki
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Li-sa Chang
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Kazuki Aochi
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Emi Meren
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Tatsuya Sakamoto
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Ryo Tomita
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Yu Higaki
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Naoto Osugi
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Aya Sugimoto
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Kei Takahashi
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Kaori Mukai
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Kengo Matsumoto
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Shiro Hayashi
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Sachiko Nakajima
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Masashi Yamamoto
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
,
Koji Fukui
,
Masami Inada
Department of Gastroenterology, Toyonaka Municipal Hospital, Osaka, Japan
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Abstract

Background and study aims The relationship between acute colonic diverticulitis and colorectal cancer (CRC) is unclear, but colonoscopy is recommended to exclude malignancy. We compared the detection rates for colorectal neoplasia in patients with colonic diverticulitis and asymptomatic patients who had positive fecal immunochemical tests (FITs).

Patients and methods In total, 282 patients with acute colonic diverticulitis were hospitalized in our hospital from February 2011 to December 2019. Of them, 143 patients with diverticulitis and 1819 with positive FITs patients during the same period underwent colonoscopy without a prior colonoscopy within 5 years. We retrospectively compared these patients in terms of the invasive CRC rate, advanced neoplasia detection rate (ANDR), adenoma detection rate (ADR), and polyp detection rate (PDR).

Results Compared to the diverticulitis group, the FIT-positive group had a significantly higher CRC rate (0 vs 2.7 %, P = 0.0061), ANDR (5.6 vs. 14.0 %, P = 0.0017), ADR (19.6 vs. 53.2 %, P < .0001), and PDR (44.1 vs. 91.0 %, P < .0001). Using 1:1 propensity score matching based on age and sex, we obtained 276 matched patients in both groups. After matching, no difference was found in the CRC rate (0 vs 0.7 %) or ANDR (5.8 vs 7.3 %) between groups, but the ADR and PDR were significantly higher in the FIT-positive group (20.3 vs 43.5 %, P < .0001; 45.7 % vs 86.2 %, P < .0001).

Conclusion Patients with acute diverticulitis had lower ADRs and PDRs than patients with positive FITs.



Publikationsverlauf

Eingereicht: 30. Juni 2020

Angenommen: 02. November 2020

Artikel online veröffentlicht:
18. Februar 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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