Zeitschrift für Phytotherapie, Table of Contents Zeitschrift für Phytotherapie 2022; 43(03): 121-127DOI: 10.1055/a-1664-6464 Forschung Der Hase im Pfeffer [1] – Gewürze aus medizinischer Sicht Detmar Jobst 1 Bonn › Author Affiliations Recommend Article Abstract Buy Article Full Text References Literatur 1 Gesellschaft für deutsche Sprache e.V. Was bedeutet Da liegt der Hase im Pfeffer? https://gfds.de/da-liegt-der-hase-im-pfeffer/ 2 Jobst D, Mücke M. DEGAM. Knieschmerzen bei Arthrosezeichen. S1-Leitlinie. AWMF-Register-Nr. 053-050. Stand: 11/2017 3 Patel SS, Acharya A, Ray RS. et al. Cellular and molecular mechanisms of curcumin in prevention and treatment of disease. Crit Rev Food Sci Nutr 2020; 60: 887-939 4 Salehi B, Stojanović-Radić Z, Matejić J. et al. The therapeutic potential of curcumin: A review of clinical trials. Eur J Med Chem 2019; 163: 527-545 5 Shamsi S, Tran H, Tan RS. et al. Curcumin, piperine, and capsaicin: a comparative study of spice-mediated inhibition of human cytochrome P450 isozyme activities. Drug Metab Dispos 2017; 45: 49-55 6 Volak LP, Ghirmai S, Cashman JR, Court MH. Curcuminoids inhibit multiple human cytochromes P450 (CYP), UDP-glucuronosyltransferase (UGT), and sulfotransferase (SULT) enzymes. Drug Metab Dispos Biol Fate Chem 2008; 36: 1594-1605 7 Soleimani V, Sahebkar A, Hosseinzadeh H. Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review. Phytother Res 2018; 32: 985-995 8 Dei Cas M, Ghidoni R. Dietary curcumin: correlation between bioavailability and health potential. Nutrients 2019; 11: 2147 9 European Medicines Agency. . Assessment report on Curcuma longa L., rhizoma. EMA/HMPC/749518/2016. S. 23. https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-curcuma-longa-l-rhizoma-revision-1_en.pdf;Zugriff: 20.12.2021 10 Kwiecien S, Magierowski M, Majka J. et al. Curcumin, a potent protectant against esophageal and gastric disorders. Int J Mol Sci 2019; 20: 1477 11 European Medicines Agency.. European Union herbal monograph on Curcuma longa L., rhizome. EMA/HMPC/329755/2017 12 European Medicines Agency. . Herbal medicinal products. https://www.ema.europa.eu/en/human-regulatory/herbal-medicinal-products; Zugriff: 03.03.2022 13 Khodir AE, Said E, Atif H. et al. Targeting Nrf2/HO-1 signaling by crocin: Role in attenuation of AA-induced ulcerative colitis in rats. Biomed Pharmacother 2019; 110: 389-399 14 Abdullaev FI. Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.). Exp Biol Med (Maywood) 2002; 227: 20-25 15 Ahmadpanah M, Ramezanshams F, Ghaleiha A. et al. Crocus Sativus L. (saffron) versus sertraline on symptoms of depression among older people with major depressive disorders – a double-blind, randomized intervention study. Psychiatry Res 2019; 282: 112613 16 European Medicines Agency. . Assessment report on Zingiber officinale Roscoe, rhizome. EMA/HMPC/577856/2010 https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-zingiber-officinale-roscoe-rhizoma_en.pdf Zugriff: 27.12.2021 17 European Medicines Agency. Ingwerwurzelstock [Zusammenfassung für die Öffentlichkeit]. EMA/HMPC/296580/2012. https://www.ema.europa.eu/en/documents/herbal-summary/ginger-summary-public_de.pdfZugriff: 27.12.2021 18 Mahboubi M. Caraway as important medicinal plants in management of diseases. Nat Prod Bioprospect 2019; 9: 1-11 19 European Medicines Agency. Addendum to Assessment report on Carum carvi L., fructus and aetheroleum. EMA/HMPC/351955/2020. https://www.ema.europa.eu/en/documents/herbal-report/addendum-assessment-report-carum-carvi-l-fructus-aetheroleum_en.pdf Zugriff: 27.12.2021 20 European Medicines Agency. European Union herbal monograph on Carum carvi L., fructus. EMA/HMPC/715092/2013. https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-carum-carvi-l-fructus_en.pdf Zugriff: 27.12.2021 21 Li J, Lv L, Zhang J. et al. A combination of peppermint oil and caraway oil for the treatment of functional dyspepsia: A systematic review and meta-analysis. Evid Based Complement Alternat Med 2019; 2019: 7654947 22 Reichling J. Gewürze mit antimikrobiellen Eigenschaften. Pharmakon 4/2021: 304–312 23 Luo CH, Zou L, Sun H. et al. A review of the anti-inflammatory effects of rosmarinic acid on inflammatory diseases. Front Pharmacol 2020; 11: 153 24 Kooperation Phytopharmaka. Arzneipflanzenlexikon: Rosmarin – Rosmarinus officinalis L. https://arzneipflanzenlexikon.info/rosmarin.php; Zugriff 21.12.2021 25 European Medicines Agency. Community herbal monograph on Rosmarinus officinalis L., folium. EMA/HMPC/13633/2009. https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-rosmarinus-officinalis-l-folium_en.pdf Zugriff: 21.12.2021 26 European Medicines Agency. Assessment report on Salvia officinalis L., folium and Salvia officinalis L., aetheroleum. EMA/HMPC/150801/2015 https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-salvia-officinalis-l-folium-salvia-officinalis-l-aetheroleum-revision-1_en.pdf Zugriff: 21.12.2021 27 European Medicines Agency. European Union herbal monograph on Salvia officinalis L., folium. EMA/HMPC/277152/2015. https://www.ema.europa.eu/en/documents/herbal-monograph/draft-european-union-herbal-monograph-salvia-officinalis-l-folium_en.pdf Zugriff: 28.12.2021 28 Srinivasan K. Biological activities of red pepper. Crit Rev Food Sci Nutr 2016; 56: 1488-1500 29 Batiha GE, Alqahtani A, Ojo OA. et al. Biological properties, bioactive constituents, and pharmacokinetics of some Capsicum spp. and capsaicinoids. Int J Mol Sci 2020; 21: 5179 30 Shityakov S, Bigdelian E, Hussein AA. et al. Phytochemical and pharmacological attributes of piperine: A bioactive ingredient of black pepper. Eur J Med Chem 2019; 176: 149-161 31 European Medicines Agency. European Union herbal monograph on Capsicum annuum L. var. minimum (Miller) Heiser and small fruited varieties of Capsicum frutescens L., fructus. EMA/HMPC/674139/2013. https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-capsicum-annuum-l-var-minimum-miller-heiser-small-fruited_en.pdf Zugriff: 28.12.2021 32 Jobst D, Hensel A, Kraft K. Positionspapier der Gesellschaft für Phytotherapie zur Abgrenzung von pflanzlichen Arzneimitteln und Nahrungsergänzungsmitteln. Z Phytother 2021; 42: 188-191 33 Europäische Health-Claims-Verordnung (EG) Nr. 1924/2006 34 Bilia AR, Costa MDC. Medicinal plants and their preparations in the European market: Why has the harmonization failed? The cases of St. John’s wort, valerian, ginkgo, ginseng, and green tea. Phytomedicine 2021; 81: 153421
