Trainingsinduzierte Hypoalgesie: Mit Bewegung gegen den Schmerz

Bei vielen muskuloskelettalen Beschwerden lindert Bewegung die Schmerzen und verbessert die Funktionsfähigkeit. Körperliche Aktivität zeigt aber auch systemische Effekte, die sich positiv auf die Psyche und mehrere Organsysteme auswirken können.

Publication History

Article published online:
06 April 2022

• Literatur

• 1 Naugle KM, Fillingim RB. Riley JL3rd. A meta-analytic review of the hypoalgesic effects of exercise. J Pain 2012; (12) 1139-1150 DOI: 10.1016/j.jpain.2012.09.006.
• 2 Da Silva Santos R, Galdino G. Endogenous systems involved in exercise-induced analgesia. J Physiol Pharmacol 2018; 69 (01) 3-13 DOI: 10.26402/jpp.2018.1.0.
• 3 Rice D, Nijs J, Kosek E. et al. Exercise-Induced Hypoalgesia in Pain-Free and Chronic Pain Populations: State of the Art and Future Directions. J Pain 2019; 20 (11) 1249-1266 DOI: 10.1016/j.jpain.2019.03.005.
• 4 Nijs J, Kosek E, Van Oosterwijck J. et al. Dysfunctional endogenous analgesia during exercise in patients with chronic pain: to exercise or not to exercise?. Pain Physician 2012; 15 (3 Suppl): ES205-13
• 5 Alfredson H, Pietilä T, Jonsson P. et al. Heavy-load eccentric calf muscle training for the treatment of chronic Achilles tendinosis. Am J Sports Med 1998; 26 (03) 360-366 DOI: 10.1177/03635465980260030301.
• 6 Silbernagel KG, Thomeé R, Eriksson BI. et al. Continued sports activity, using a pain-monitoring model, during rehabilitation in patients with Achilles tendinopathy: a randomized controlled study. Am J Sports Med 2007; 3 – 5 (6): 897906 DOI: 10.1177/0363546506298279.
• 7 Smith BE, Hendrick P, Smith TO. et al. Should exercises be painful in the management of chronic musculoskeletal pain? A systematic review and meta-analysis. Br J Sports Med 2017; 51 (23) 1679-1687 DOI: 10.1136/bjsports-2016-097383.
• 8 Smith BE, Hendrick P, Bateman M. et al. Musculoskeletal pain and exercise-challenging existing paradigms and introducing new. Br J Sports Med 2019; 53 (14) 907-912 DOI: 10.1136/bjsports-2017-098983.
• 9 Collins KH, Herzog W, MacDonald GZ. et al. Obesity, Metabolic Syndrome, and Musculoskeletal Disease: Common Inflammatory Pathways Suggest a Central Role for Loss of Muscle Integrity. Front Physiol 2018; 9: 112 DOI: 10.3389/fphys.2018.00112.
• 10 Kauppila LI. Atherosclerosis and disc degeneration/low-back pain-a systematic review. Eur J Vasc Endovasc Surg 2009; 37 (06) 661-670 DOI: 10.1016/j.ejvs.2009.02.006.
• 11 Misra D, Fielding RA, Felson DT. et al. Risk of Knee Osteoarthritis With Obesity, Sarcopenic Obesity, and Sarcopenia. Arthritis Rheumatol 2019; 71 (02) 232-237 DOI: 10.1002/art.40692.
• 12 Tilley BJ, Cook JL, Docking SI. et al. Is higher serum cholesterol associated with altered tendon structure or tendon pain? A systematic review. Br J Sports Med 2015; 49 (23) 1504-1509 DOI: 10.1136/bjsports-2015-095100.
• 13 Pedersen BK. Anti-inflammatory effects of exercise: role in diabetes and cardiovascular disease. Eur J Clin Invest 2017; 47 (08) 600-611 DOI: 10.1111/eci.12781.
• 14 Abate M, Salini V, Andia I. How Obesity Affects Tendons?. Adv Exp Med Biol 2016; 920: 167-177
• 15 Samartzis D, Karppinen J, Cheung JP. et al. Disk degeneration and low back pain: are they fat-related conditions?. Global Spine J 2013; 3 (03) 133-144 DOI: 10.1055/s-0033-1350054.
• 16 Ranger TA, Wong AM, Cook JL. et al. Is there an association between tendinopathy and diabetes mellitus? A systematic review with meta-analysis. Br J Sports Med 2016; 50 (16) 982-989 DOI: 10.1136/bjsports-2015-094735.
• 17 Zreik NH, Malik RA, Charalambous CP. Adhesive capsulitis of the shoulder and diabetes: a meta-analysis of prevalence. Muscles Ligaments Tendons J 2016; 6 (01) 26-34 DOI: 10.11138/mltj/2016.6.1.026.
• 18 Veronese N, Cooper C, Reginster JY. et al. Type 2 diabetes mellitus and osteoarthritis. Semin Arthritis Rheum 2019; 49 (01) 9-19
• 19 Paley CA, Johnson MI. Physical Activity to Reduce Systemic Inflammation Associated With Chronic Pain and Obesity: A Narrative Review. Clin J Pain 2016; 32 (04) 365-370 DOI: 10.1097/AJP.0000000000000258.
• 20 Lutke Schipholt IJ, Scholten-Peeters GGM, Bontkes HJ. et al. Multiple confounders influence the association between low-grade systemic inflammation and musculoskeletal pain. A call for a prudent interpretation of the literature. Spine J 2018; 18 (11) 2162-2163 DOI: 10.1016/j.spinee.2018.07.019.
• 21 Liu Y, Ding W, Wang HL. et al. Gut microbiota and obesity-associated osteoarthritis. Osteoarthritis Cartilage 2019; 27 (09) 1257-1265 DOI: 10.1016/j.joca.2019.05.009.
• 22 Rohleder N. Stress and inflammation – The need to address the gap in the transition between acute and chronic stress effects. Psychoneuroendocrinology 2019; 105: 164-171 DOI: 10.1016/j.psyneuen.2019.02.021.
• 23 Leal LG, Lopes MA, Batista Jr. ML. Physical Exercise-Induced Myokines and Muscle-Adipose Tissue Crosstalk: A Review of Current Knowledge and the Implications for Health and Metabolic Diseases. Front Physiol 2018; 9: 1307 DOI: 10.3389/fphys.2018.01307.
• 24 Szychlinska MA, Di Rosa M, Castorina A. et al. A correlation between intestinal microbiota dysbiosis and osteoarthritis. Heliyon 2019; 5 (01) e01134 DOI: 10.1016/j.heliyon.2019.e01134.
• 25 Mailing LJ, Allen JM, Buford TW. et al. Exercise and the Gut Microbiome: A Review of the Evidence, Potential Mechanisms, and Implications for Human Health. Exerc Sport Sci Rev 2019; 47 (02) 75-85 DOI: 10.1249/JES.0000000000000183.
• 26 Zdziarski LA, Wasser JG, Vincent HK. Chronic pain management in the obese patient: a focused review of key challenges and potential exercise solutions. J Pain Res 2015; 8: 63-77 DOI: 10.2147/JPR.S55360.