CC BY-NC-ND 4.0 · Dtsch Med Wochenschr 2022; 147(14): 62-69
DOI: 10.1055/a-1821-5994
Originalarbeit

Eine Querschnittsuntersuchung zur Qualität der Sauerstofftherapie in drei deutschen Krankenhäusern

A cross-sectional study in three German hospitals regarding oxygen therapy characteristics
Oana Joean
1   Klinik für Pneumologie, Medizinische Hochschule Hannover
,
Maria Petronella vanʼt Klooster
2   Klinik für Pneumologie und Beatmungsmedizin, Krankenhaus Siloah, Klinikum Region Hannover
,
Moritz Z. Kayser
1   Klinik für Pneumologie, Medizinische Hochschule Hannover
,
Christina Valtin
1   Klinik für Pneumologie, Medizinische Hochschule Hannover
,
Raphael Ewen
1   Klinik für Pneumologie, Medizinische Hochschule Hannover
,
Heiko Golpon
1   Klinik für Pneumologie, Medizinische Hochschule Hannover
3   Deutsches Zentrum für Lungenforschung (DZL), Biomedical Research in End-Stage and Obstructive Lung Disease (BREATH), Hannover
,
Thomas Fühner
2   Klinik für Pneumologie und Beatmungsmedizin, Krankenhaus Siloah, Klinikum Region Hannover
,
Jens Gottlieb
1   Klinik für Pneumologie, Medizinische Hochschule Hannover
3   Deutsches Zentrum für Lungenforschung (DZL), Biomedical Research in End-Stage and Obstructive Lung Disease (BREATH), Hannover
› Author Affiliations

Zusammenfassung

Einleitung Sauerstoff (O2) ist eines der am häufigsten angewendeten Arzneimittel in deutschen Krankenhäusern und im Rettungswesen. Sowohl eine Hypoxämie als auch eine Hyperoxämie sind mit Komplikationen vergesellschaftet. In Deutschland fehlen bislang belastbare Daten zur Anwendung, Dokumentation und Überwachung der O2-Therapie.

Methoden Eine Querschnittsstudie zur Sauerstoff-Anwendung wurde in 3 Krankenhäusern der maximalen bzw. supramaximalen Versorgung in Hannover im Herbst 2020 durchgeführt.

Ergebnisse Von 343 erfassten Patienten erhielten 20 % eine O2-Therapie. Bei 29 % der Patienten mit O2-Therapie bestand ein Hyperkapnie-Risiko. Lediglich bei 68 % Patienten mit einer O2-Therapie lag eine SOP zur O2-Anwendung auf den jeweiligen Stationen vor und nur bei 22 % entsprach die gegebene O2-Therapie dem tatsächlichen Bedarf des Patienten. Nur bei 30 % des Gesamtkollektivs und 41 % der Patienten mit O2-Therapie erfolgte eine vollständige Dokumentation der Vitalparameter. Eine Überwachung der O2-Therapie mittels arterieller oder kapillärer Blutgasanalyse (BGA) erfolgte bei 76 % der O2-Patienten. Hier zeigte sich bei 64 % der Patienten eine Normoxämie, bei 17 % eine Hyperoxämie und bei 19 % eine Hypoxämie. Der einzige identifizierbare Prediktor für eine adäquate O2-Therapie war eine vorangegangene Beatmungstherapie.

Diskussion Insgesamt zeigt sich eine suboptimale Indikationsstellung, Anwendung und Kontrolle der Sauerstofftherapie. Schulungen des pflegerischen und ärztlichen Personals zur Verbesserung der Anwendung der O2-Therapie und resultierend auch der Patientensicherheit sind dringend notwendig.

Abstract

Background Oxygen (O2) therapy is one of the most commonly applied medications in German hospitals and rescue services. Both hypoxemia and hyperoxemia can be associated with complications. There is currently a lack of reliable data on the use, documentation and surveillance of O2-therapy in German hospitals.

Methods We conducted a cross-sectional study on the use of O2 in three hospitals in Hannover, Germany.

Results Of 343 patients included in this study, 20 % received O2 therapy. Twenty-nine percent of patients receiving O2 were at increased risk for hypercapnia. A standard operating procedure (SOP) for O2 therapy was available in only 68 % of patients. In 22 % patients the applied O2-therapy was appropriate in the context of the documented vital parameters. A complete documentation of vital parameters was conducted in only 30 % of all patients and 41 % of patients receiving O2-therapy. A surveillance of O2-therapy using capillary or arterial blood gas analysis was performed in 76 % of patients. Here, 64 % of patients showed normoxemia, 17 % showed hyperoxemia and 19 % of patients showed hypoxemia. The only identifiable predictor for an adequate O2-therapy was a previous invasive ventilation.

Discussion Our data point towards and inadequate prescription, application and documentation of O2 therapy. The recently released German S3-guideline should be used to increase awareness among physicians and nursing staff regarding the use of O2-therapy to improve O2 therapy and consequently patient safety.



Publication History

Article published online:
22 July 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • Literatur

  • 1 OʼDriscoll BR, Howard LS, Earis J. et al. BTS guideline for oxygen use in adults in healthcare and emergency settings. Thorax 2017; 72: ii1-ii90
  • 2 OʼDriscoll R. British Thoracic Society Emergency Oxygen Audit Report National Audit Period: 15 August – 1 November 2015. In; 2016
  • 3 Beasley R, Mackle D. Increased risk of mortality with liberal oxygen therapy compared with conservative oxygen therapy in critically ill adults. BMJ Evidence-Based Medicine 2019; 24: 113-114
  • 4 Chu DK, Kim LHY, Young PJ. et al. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. The Lancet 2018; 391: 1693-1705
  • 5 Turner CE, Barker-Collo SL, Connell CJ. et al. Acute hypoxic gas breathing severely impairs cognition and task learning in humans. Physiol Behav 2015; 142: 104-110
  • 6 Curtis BR, Rak KJ, Richardson A. et al. Perceptions of Hyperoxemia and Conservative Oxygen Therapy in the Management of Acute Respiratory Failure. Ann Am Thorac Soc 2021; 18: 1369-1379
  • 7 Schjørring OL, Perner A, Wetterslev J. et al. Handling Oxygenation Targets in the Intensive Care Unit (HOT‐ICU) – Protocol for a randomised clinical trial comparing a lower vs a higher oxygenation target in adults with acute hypoxaemic respiratory failure. Acta Anaesthesiologica Scandinavica 2019;
  • 8 Gottlieb J, Capetian P, Hamsen U. et al. [German S3 Guideline – Oxygen Therapy in the Acute Care of Adult Patients]. Pneumologie 2021;
  • 9 Beasley R, Chien J, Douglas J. et al. Thoracic Society of Australia and New Zealand oxygen guidelines for acute oxygen use in adults: “Swimming between the flags”. Respirology 2015; 20: 1182-1191
  • 10 MacIntyre NR. Tissue hypoxia: implications for the respiratory clinician. Respir Care 2014; 59: 1590-1596
  • 11 Hanson 3rd CW, Marshall BE. et al. Causes of hypercarbia with oxygen therapy in patients with chronic obstructive pulmonary disease. Crit Care Med 1996; 24: 23-28
  • 12 Barbateskovic M, Schjørring OLL, Jakobsen JC. et al. Higher versus lower inspiratory oxygen fraction or targets of arterial oxygenation for adult intensive care patients. Cochrane Database of Systematic Reviews 2017;
  • 13 Edmark L, Kostova-Aherdan K, Enlund M. et al. Optimal oxygen concentration during induction of general anesthesia. Anesthesiology 2003; 98: 28-33
  • 14 Farquhar H, Weatherall M, Wijesinghe M. et al. Systematic review of studies of the effect of hyperoxia on coronary blood flow. Am Heart J 2009; 158: 371-377
  • 15 Cousins JL, Wark PA, McDonald VM. Acute oxygen therapy: a review of prescribing and delivery practices. Int J Chron Obstruct Pulmon Dis 2016; 11: 1067-1075
  • 16 Parke RL, Eastwood GM, McGuinness SP. et al. Oxygen therapy in non-intubated adult intensive care patients: a point prevalence study. Crit Care Resusc 2013; 15: 287-293
  • 17 Kamran A, Chia E, Tobin C. Acute oxygen therapy: an audit of prescribing and delivery practices in a tertiary hospital in Perth, Western Australia. Intern Med J 2018; 48: 151-157
  • 18 Medford A, Bowen J, Harvey J. Improved oxygen prescribing using a nurse-facilitated reminder. Br J Nurs 2009; 18: 730-734
  • 19 Heartshorne R, Cardell J, OʼDriscoll R. et al. Implementing target range oxygen in critical care: A quality improvement pilot study. J Intensive Care Soc 2021; 22: 17-26
  • 20 Helmerhorst HJ, Schultz MJ, van der Voort PH. et al. Effectiveness and Clinical Outcomes of a Two-Step Implementation of Conservative Oxygenation Targets in Critically Ill Patients: A Before and After Trial. Crit Care Med 2016; 44: 554-563
  • 21 Gunathilake R, Lowe D, Wills J. et al. Implementation of a multicomponent intervention to optimise patient safety through improved oxygen prescription in a rural hospital. Aust J Rural Health 2014; 22: 328-333
  • 22 Cousins JL, Wark PA, McDonald VM. Acute oxygen therapy: a review of prescribing and delivery practices. Int J Chron Obstruct Pulmon Dis 2016; 11: 1067-1075
  • 23 Goodacre S, Turner J, Nicholl J. Prediction of mortality among emergency medical admissions. Emerg Med J 2006; 23: 372-375
  • 24 Bleyer AJ, Vidya S, Russell GB. et al. Longitudinal analysis of one million vital signs in patients in an academic medical center. Resuscitation 2011; 82: 1387-1392
  • 25 Masson H, Stephenson J. Investigation into the predictive capability for mortality and the trigger points of the National Early Warning Score 2 (NEWS2) in emergency department patients. Emerg Med J 2021;
  • 26 Prasad PA, Fang MC, Martinez SP. et al. Identifying the Sickest During Triage: Using Point-of-Care Severity Scores to Predict Prognosis in Emergency Department Patients With Suspected Sepsis. J Hosp Med 2021; 16: 453-461
  • 27 Leuvan CH, Mitchell I. Missed opportunities? An observational study of vital sign measurements. Crit Care Resusc 2008; 10: 111-115
  • 28 McGain F, Cretikos MA, Jones D. et al. Documentation of clinical review and vital signs after major surgery. Med J Aust 2008; 189: 380-383
  • 29 Hogan J. Why donʼt nurses monitor the respiratory rates of patients?. Br J Nurs 2006; 15: 489-492
  • 30 Philip KE, Pack E, Cambiano V. et al. The accuracy of respiratory rate assessment by doctors in a London teaching hospital: a cross-sectional study. J Clin Monit Comput 2015; 29: 455-460
  • 31 Nguyen B, Gunaratne Y, Kemp T. et al. The Oxygen project: a prospective study to assess the effectiveness of a targeted intervention to improve oxygen management in hospitalised patients. Intern Med J 2021; 51: 660-665
  • 32 Schjorring OL, Klitgaard TL, Perner A. et al. Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure. N Engl J Med 2021; 384: 1301-1311