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CC BY-NC-ND 4.0 · Endosc Int Open 2022; 10(07): E978-E981
DOI: 10.1055/a-1839-5401
Original article

Endoscopic management of tumors of minor ampulla: a multicenter study

Ahamed A. Khalyfa
1   Franciscan Saint James Health Olympia Fields Campus, Gastroenterology
,
Nayab Ahsan
2   Southwest Gastroenterology, Gastroenterology
,
Mahnoor Inam
2   Southwest Gastroenterology, Gastroenterology
,
Kamran Ayub
3   Silver Cross Hospital, Gastroenterology
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Abstract

Background and study aims Papillary and duodenal carcinoma are aggressive cancers with poor 5-year survival rates. Papillectomy is a well-established treatment for early-stage carcinoma of the major papilla. Tumors arising in the minor papilla are relatively rare and there is little research available on the endoscopic management of these tumors.

Patients and methods The purpose of this study was to establish the safety and efficacy of endoscopic papillectomy in the management of minor papillary tumors. A total of six patients undergoing ERCP for papillectomy for minor papillary tumor at four hospitals were included in this study over a period of 5 years.

Results Papillectomy was technically successful in all six patients. Pathology revealed adenoma in three patients, adenoma with high-grade dysplasia in one patient, carcinoma in one patient, and carcinoid tumor in one patient. For follow-up, one patient had an additional tumor identified at 2 years which was found to be a recurrence of the original adenoma. This patient was treated with repeat papillectomy with no further evidence of recurrence.

Conclusions In our pilot study, we demonstrate that endoscopic papillectomy appears safe and effective in the management of minor papillary tumors.



Publication History

Received: 15 December 2021

Accepted after revision: 20 April 2022

Article published online:
15 July 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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