Ultraschall Med 2022; 43(05): 436-455
DOI: 10.1055/a-1891-6421
Continuing Medical Education

The Role of Ultrasound in Chronic Intestinal Diseases in Pediatric Patients

Die Rolle des Ultraschalls bei chronischen Darmerkrankungen von Kindern und Jugendlichen
Gianfranco Vallone
1   Radiodiagnostic, University of Molise, Department of Medicine and Health Sciences Vincenzo Tiberio, Campobasso, Italy
,
Paolo Pizzicato
2   Radiology, Federico II University Hospital, Napoli, Italy
,
Eugenio Rossi
3   Radiodiagnostic, A.O.R.N. Santobono-Pausilipon, Napoli, Italy
,
Luca Brunese
1   Radiodiagnostic, University of Molise, Department of Medicine and Health Sciences Vincenzo Tiberio, Campobasso, Italy
› Author Affiliations

Abstract

Chronic inflammatory bowel diseases (IBD) are chronic disorders of the gastrointestinal tract, with an increasing incidence in pediatric populations. Ultrasound of the intestinal wall represents the first-line imaging technique in children since it is a noninvasive method, is free of ionizing radiation, and is inexpensive. Furthermore, the absence of intestinal wall thickening has a good negative predictive value for IBD, which is greater for Crohn’s disease than for ulcerative colitis. Ultrasound is used for the diagnosis of disease, for the differential diagnosis in IBD, in the follow-up of known IBD, in the definition of the site and extent of the disease, for the diagnosis of intestinal complications, for the evaluation of disease activity, in the definition of prognostic parameters, and in the post-operative follow-up.

Zusammenfassung

Chronisch entzündliche Darmerkrankungen (CED) sind chronische Erkrankungen des Magen-Darm-Trakts, mit zunehmender Inzidenz bei Kindern und Jugendlichen. Die Ultraschalluntersuchung der Darmwand ist bei Kindern die Erstlinienmethode, da sie nichtinvasiv, strahlenfrei und kostengünstig ist. Außerdem hat das Fehlen einer Darmwandverdickung bei CED einen guten negativen Vorhersagewert, der bei Morbus Crohn höher als bei Colitis ulcerosa ist. Ultraschall wird eingesetzt zur Erstdiagnose, zur Differenzialdiagnose bei CED, zur Verlaufskontrolle bei bekannter CED, zur Bestimmung von Lokalisation und Ausmaß der Erkrankung, zur Diagnose von Darmkomplikationen, zur Bewertung der Krankheitsaktivität, zur Bestimmung prognostischer Parameter und zur postoperativen Nachsorge.



Publication History

Article published online:
05 October 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Rosen MJ, Dhawan A, Saeed SA. Inflammatory Bowel Disease in Children and Adolescents. JAMA Pediatr 2015; 169 (11) 1053-1060
  • 2 Lakatos PL. Recent trends in the epidemiology of inflammatory bowel diseases: up or down?. World J Gastroenterol 2006; 12 (38) 6102-6128
  • 3 Malaty HM, Fan X, Opekun AR. et al. Rising incidence of inflammatory bowel disease among children: a 12-year study. J Pediatr Gastroenterol Nutr 2010; 50 (01) 27-31
  • 4 Ruemmele FM, El Khoury MG, Talbotec C. et al. Characteristics of inflammatory bowel disease with onset during the first year of life. J Pediatr Gastroenterol Nutr 2006; 43 (05) 603-609
  • 5 Aziz DA, Moin M, Majeed A. et al. Paediatric Inflammatory Bowel Disease: Clinical Presentation and Disease Location. Pak J Med Sci 2017; 33 (04) 793-797
  • 6 Beattie RM, Croft NM, Fell JM. et al. Inflammatory bowel disease. Arch Dis Child 2006; 91 (05) 426-432
  • 7 Yu YR, Rodriguez JR. Clinical presentation of Crohn’s, ulcerative colitis, and indeterminate colitis: Symptoms, extraintestinal manifestations, and disease phenotypes. Semin Pediatr Surg 2017; 26 (06) 349-355
  • 8 Timmer A, Behrens R, Buderus S. et al. Childhood onset inflammatory bowel disease: predictors of delayed diagnosis from the CEDATA German-language pediatric inflammatory bowel disease registry. J Pediatr 2011; 158 (03) 467-473.e2
  • 9 Oliveira SB, Monteiro IM. Diagnosis and management of inflammatory bowel disease in children. BMJ 2017; 357: j2083
  • 10 Alison M, Kheniche A, Azoulay R. et al. Ultrasonography of Crohn disease in children. Pediatr Radiol 2007; 37 (11) 1071-1082
  • 11 Strobel D, Goertz RS, Bernatik T. Diagnostics in inflammatory bowel disease: ultrasound. World J Gastroenterol 2011; 17 (27) 3192-3197
  • 12 Atkinson NS, Bryant RV, Dong Y. et al. WFUMB Position Paper. Learning Gastrointestinal Ultrasound: Theory and Practice. Ultrasound Med Biol 2016; 42 (12) 2732-2742
  • 13 O’Malley ME, Wilson SR. US of gastrointestinal tract abnormalities with CT correlation. Radiographics 2003; 23 (01) 59-72
  • 14 Gale HI, Gee MS, Westra SJ. et al. Abdominal ultrasonography of the pediatric gastrointestinal tract. World J Radiol 2016; 8 (07) 656-667
  • 15 Canani RB, de Horatio LT, Terrin G. et al. Combined use of noninvasive tests is useful in the initial diagnostic approach to a child with suspected inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2006; 42 (01) 9-15
  • 16 Biko DM, Rosenbaum DG, Anupindi SA. Ultrasound features of pediatric Crohn disease: a guide for case interpretation. Pediatr Radiol 2015; 45 (10) 1557-1566 , quiz 1554-1556.
  • 17 Calabrese E, Kucharzik T, Maaser C. et al. Real-time Interobserver Agreement in Bowel Ultrasonography for Diagnostic Assessment in Patients With Crohn’s Disease: An International Multicenter Study. Inflamm Bowel Dis 2018; 24 (09) 2001-2006
  • 18 Atkinson NSS, Bryant RV, Dong Y. et al. How to perform gastrointestinal ultrasound: Anatomy and normal findings. World J Gastroenterol 2017; 23 (38) 6931-6941
  • 19 Coelho R, Ribeiro H, Maconi G. Bowel Thickening in Crohn’s Disease: Fibrosis or Inflammation? Diagnostic Ultrasound Imaging Tools. Inflamm Bowel Dis 2017; 23 (01) 23-34
  • 20 Giles E, Hanci O, McLean A. et al. Optimal assessment of paediatric IBD with MRI and barium follow-through. J Pediatr Gastroenterol Nutr 2012; 54 (06) 758-762
  • 21 Levine A, Koletzko S, Turner D. et al. ESPGHAN revised porto criteria for the diagnosis of inflammatory bowel disease in children and adolescents. J Pediatr Gastroenterol Nutr 2014; 58 (06) 795-806