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DOI: 10.1055/a-1978-9243
Premedication with simethicone and N-acetyl cysteine in esophagogastroduodenoscopy: Is it time to use it in practice?
We read with great interest the recent article by Krishnamurthy V et al [1], evaluating simethicone and N-acetyl cysteine combination as premedication before esophagogastroduodenoscopy (EGD). We would like to congratulate the authors for conducting this study with a large sample size and with potential implication for improvement in the quality of EGD with focus on diagnostic yield and patient comfort. However, there are few areas about which we seek clarification.
Publication History
Article published online:
19 January 2023
© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Krishnamurthy V, Joseph A, Venkataraman S. et al. Simethicone and N-acetyl cysteine combination as premedication before esophagogastroduodenoscopy: Double-blind randomized controlled trial. Endosc Int Open 2022; 10: E585-E592
- 2 Elvas L, Areia M, Brito D. et al. Premedication with simethicone and N-acetylcysteine in improving visibility during upper endoscopy: a double-blind randomized trial. Endoscopy 2017; 49: 139-145