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Ultraschall Med 2023; 44(03): 240-268
DOI: 10.1055/a-1996-0767
Continuing Medical Education

Pulmonary Sonography – Neonatal Diagnosis Part 2

Article in several languages: English | deutsch
Simone Schwarz 
  Clinic for Pediatrics and Adolescent Medicine, Sana-Kliniken Duisburg GmbH, Duisburg, Germany
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Previous part of this series:

Pulmonary Sonography – Neonatal Diagnosis Part 1Ultraschall Med 2023; 44(01): 14-35
DOI: 10.1055/a-1885-5664

Abstract

A healthy, air-filled lung can only be visualized by its artifacts, and pathologies of the lung are revealed by changes in these artifacts. Because ultrasound artifacts are predominantly used in pulmonary sonography to assess pathologic processes, the variability of sonographically imageable phenomena is limited. For this reason, different pulmonary diseases may present very similarly in ultrasound. Therefore, a correct interpretation of the findings is only possible in the clinical context, taking into account the age-dependent differential diagnoses.

The particular relevance of lung ultrasound in the treatment of neonatal patients results from a close correlation between the extent of sonographically-depictable pathologies and parameters of respiratory insufficiency. This suggests a direct correlation between ultrasound findings and the severity of lung injury. Lung ultrasound thus represents a unique, ubiquitously available, bedside, serial method for monitoring the pulmonary status.



Publication History

Article published online:
20 January 2023

© 2023. Thieme. All rights reserved.

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  • References

  • 1 Raimondi F, Yousef N, Rodriguez Fanjul J. et al. A Multicenter Lung Ultrasound Study on Transient Tachypnea of the Neonate. Neonatology 2019; 115 (03) 263-268
    CrossrefPubMedGoogle Scholar
  • 2 Pang H, Zhang B, Shi J. et al. Diagnostic value of lung ultrasound in evaluating the severity of neonatal respiratory distress syndrome. Eur J Radiol 2019; 116: 186-191
    CrossrefPubMedGoogle Scholar
  • 3 Rodríguez-Fanjul J, Balcells C, Aldecoa-Bilbao V. et al. Lung Ultrasound as a Predictor of Mechanical Ventilation in Neonates Older than 32 Weeks. Neonatology 2016; 110 (03) 198-203
    CrossrefPubMedGoogle Scholar
  • 4 Liu J, Wang Y, Fu W. et al. Diagnosis of neonatal transient tachypnea and its differentiation from respiratory distress syndrome using lung ultrasound. Medicine 2014; 93 (27) e197
    CrossrefPubMedGoogle Scholar
  • 5 Vergine M, Copetti R, Brusa G. et al. Lung ultrasound accuracy in respiratory distress syndrome and transient tachypnea of the newborn. Neonatology 2014; 106 (02) 87-93
    CrossrefPubMedGoogle Scholar
  • 6 Liu J, Copetti R, Sorantin E. et al. Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus. J Vis Exp 2019; e58990
    PubMedGoogle Scholar
  • 7 Copetti R, Cattarossi L, Macagno F. et al. Lung ultrasound in respiratory distress syndrome: a useful tool for early diagnosis. Neonatology 2008; 94 (01) 52-59
    CrossrefPubMedGoogle Scholar
  • 8 Copetti R, Cattarossi L. The 'double lung point': an ultrasound sign diagnostic of transient tachypnea of the newborn. Neonatology 2007; 91 (03) 203-209
    CrossrefPubMedGoogle Scholar
  • 9 Blank DA, Kamlin COF, Rogerson SR. et al. Lung ultrasound immediately after birth to describe normal neonatal transition: an observational study. Arch Dis Child Fetal Neonatal Ed 2018; 103 (02) F157-F162
    CrossrefPubMedGoogle Scholar
  • 10 Smith LJ, McKay KO, van Asperen PP. et al. Normal development of the lung and premature birth. Paediatr Respir Rev 2010; 11 (03) 135-142
    CrossrefPubMedGoogle Scholar
  • 11 Rubarth LB, Quinn J. Respiratory Development and Respiratory Distress Syndrome. Neonatal Netw 2015; 34 (04) 231-238
    CrossrefPubMedGoogle Scholar
  • 12 Szymański P, Kruczek P, Hożejowski R. et al. Modified lung ultrasound score predicts ventilation requirements in neonatal respiratory distress syndrome. BMC Pediatr 2021; 21 (01) 17
    CrossrefPubMedGoogle Scholar
  • 13 Machado LU, Fiori HH, Baldisserotto M. et al. Surfactant deficiency in transient tachypnea of the newborn. J Pediatr 2011; 159 (05) 750-754
    CrossrefPubMedGoogle Scholar
  • 14 Autilio C, Echaide M, Benachi A. et al. A Noninvasive Surfactant Adsorption Test Predicting the Need for Surfactant Therapy in Preterm Infants Treated with Continuous Positive Airway Pressure. J Pediatr 2017; 182: 66-73.e1
    CrossrefPubMedGoogle Scholar
  • 15 Gregorio-Hernández R, Arriaga-Redondo M, Pérez-Pérez A. et al. Lung ultrasound in preterm infants with respiratory distress: experience in a neonatal intensive care unit. Eur J Pediatr 2020; 179 (01) 81-89
    CrossrefPubMedGoogle Scholar
  • 16 Rodriguez-Fanjul J, Jordan I, Balaguer M. et al. Early surfactant replacement guided by lung ultrasound in preterm newborns with RDS: the ULTRASURF randomised controlled trial. Eur J Pediatr 2020; 179 (12) 1913-1920
    CrossrefPubMedGoogle Scholar
  • 17 Brat R, Yousef N, Klifa R. et al. Lung Ultrasonography Score to Evaluate Oxygenation and Surfactant Need in Neonates Treated With Continuous Positive Airway Pressure. JAMA Pediatr 2015; 169 (08) e151797
    CrossrefPubMedGoogle Scholar
  • 18 Raimondi F, Migliaro F, Sodano A. et al. Use of neonatal chest ultrasound to predict noninvasive ventilation failure. Pediatrics 2014; 134 (04) e1089-e1094
    CrossrefPubMedGoogle Scholar
  • 19 Raimondi F, Migliaro F, Corsini I. et al. Neonatal Lung Ultrasound and Surfactant Administration: A Pragmatic, Multicenter Study. Chest 2021; 160 (06) 2178-2186
    CrossrefPubMedGoogle Scholar
  • 20 De Martino L, Yousef N, Ben-Ammar R. et al. Lung Ultrasound Score Predicts Surfactant Need in Extremely Preterm Neonates. Pediatrics 2018; 142 (03) e20180463
    CrossrefPubMedGoogle Scholar
  • 21 Raschetti R, Yousef N, Vigo G. et al. Echography-Guided Surfactant Therapy to Improve Timeliness of Surfactant Replacement: A Quality Improvement Project. J Pediatr 2019; 212: 137-143.e1
    CrossrefPubMedGoogle Scholar
  • 22 Elsayed YN, Hinton M, Graham R. et al. Lung ultrasound predicts histological lung injury in a neonatal model of acute respiratory distress syndrome. Pediatr Pulmonol 2020; 55 (11) 2913-2923
    CrossrefPubMedGoogle Scholar
  • 23 Raimondi F, Migliaro F, Corsini I. et al. Lung Ultrasound Score Progress in Neonatal Respiratory Distress Syndrome. Pediatrics 2021; 147 (04) e2020030528 DOI: 10.1542/peds.2020-030528.
    CrossrefPubMedGoogle Scholar
  • 24 Alonso-Ojembarrena A, Lubián-López SP. Lung ultrasound score as early predictor of bronchopulmonary dysplasia in very low birth weight infants. Pediatr Pulmonol 2019; 54 (09) 1404-1409
    CrossrefPubMedGoogle Scholar
  • 25 Loi B, Vigo G, Baraldi E. et al. Lung Ultrasound to Monitor Extremely Preterm Infants and Predict Bronchopulmonary Dysplasia. A Multicenter Longitudinal Cohort Study. Am J Respir Crit Care Med 2021; 203 (11) 1398-1409
    CrossrefPubMedGoogle Scholar
  • 26 Alonso-Ojembarrena A, Serna-Guerediaga I, Aldecoa-Bilbao V. et al. The Predictive Value of Lung Ultrasound Scores in Developing Bronchopulmonary Dysplasia: A Prospective Multicenter Diagnostic Accuracy Study. Chest 2021; 160 (03) 1006-1016
    CrossrefPubMedGoogle Scholar
  • 27 Gao S, Xiao T, Ju R. et al. The application value of lung ultrasound findings in preterm infants with bronchopulmonary dysplasia. Transl Pediatr 2020; 9 (02) 93-100
    CrossrefPubMedGoogle Scholar
  • 28 Hoshino Y, Arai J, Miura R. et al. Lung Ultrasound for Predicting the Respiratory Outcome in Patients with Bronchopulmonary Dysplasia. Am J Perinatol 2020; DOI: 10.1055/s-0040-1721848.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 29 Acosta CM, Maidana GA, Jacovitti D. et al. Accuracy of transthoracic lung ultrasound for diagnosing anesthesia-induced atelectasis in children. Anesthesiology 2014; 120 (06) 1370-1379
    CrossrefPubMedGoogle Scholar
  • 30 Chaari A, Bousselmi K, Assar W. et al. Usefulness of ultrasound in the management of acute respiratory distress syndrome. Int J Crit Illn Inj Sci 2019; 9 (01) 11-15
    CrossrefPubMedGoogle Scholar
  • 31 Liu J, Liu F, Liu Y. et al. Lung ultrasonography for the diagnosis of severe neonatal pneumonia. Chest 2014; 146 (02) 383-388
    CrossrefPubMedGoogle Scholar
  • 32 Dietrich CF, Buda N, Ciuca IM. et al. Lung ultrasound in children, WFUMB review paper (part 2). Med Ultrason 2021; 23 (04) 443-452
    CrossrefPubMedGoogle Scholar
  • 33 Tusor N, De Cunto A, Basma Y. et al. Ventilator-associated pneumonia in neonates: the role of point of care lung ultrasound. Eur J Pediatr 2021; 180 (01) 137-146
    CrossrefPubMedGoogle Scholar
  • 34 Jaworska J, Buda N, Ciuca IM. et al. Ultrasound of the pleura in children, WFUMB review paper. Med Ultrason 2021; 23 (03) 339-347
    CrossrefPubMedGoogle Scholar
  • 35 Dahmarde H, Parooie F, Salarzaei M. Accuracy of Ultrasound in Diagnosis of Pneumothorax: A Comparison between Neonates and Adults-A Systematic Review and Meta-Analysis. Can Respir J 2019; 2019: 5271982
    CrossrefPubMedGoogle Scholar
  • 36 Volpicelli G, Boero E, Sverzellati N. et al. Semi-quantification of pneumothorax volume by lung ultrasound. Intensive Care Med 2014; 40 (10) 1460-1467
    CrossrefPubMedGoogle Scholar
  • 37 Zhao M, Huang XM, Niu L. et al. Lung Ultrasound Score Predicts the Extravascular Lung Water Content in Low-Birth-Weight Neonates with Patent Ductus Arteriosus. Med Sci Monit 2020; 26: e921671
    CrossrefPubMedGoogle Scholar
  • 38 Liu J, Cao HY, Fu W. Lung ultrasonography to diagnose meconium aspiration syndrome of the newborn. J Int Med Res 2016; 44 (06) 1534-1542
    CrossrefPubMedGoogle Scholar
  • 39 Tonelotto B, Pereira SM, Tucci MR. et al. Intraoperative pulmonary hyperdistention estimated by transthoracic lung ultrasound: A pilot study. Anaesth Crit Care Pain Med 2020; 39 (06) 825-831
    CrossrefPubMedGoogle Scholar