Synlett 2024; 35(05): 485-499
Copper-(Photo)Catalyzed Radical Reactions with Organic Halides
,
Funding was provided by the Université libre de Bruxelles (ULB) (ARC grant ENLIGHTEN ME), the Fonds de la Recherche Scientifique (FNRS) (PDR T.0160.18, ‘Chargé de recherches’ and ‘Collaborateur scientifique’ fellowships to C.T.), the Federal Excellence of Science (EoS) Program (BIOFACT, Grant no. O019618F), the Région de Bruxelles Capitale – Innoviris (2019-BRIDGE-5 PhotoCop), the Fonds pour la formation à la Recherche dans l’Industrie et dans l’Agriculture (F.R.I.A.) and Oril Industrie (affiliated to Les Laboratoires Servier).
Dedicated to Paul Knochel on the occasion of his retirement.
Abstract
Copper is one of the most efficient and attractive metals for catalysis. In addition to their availability, low cost and limited toxicity, copper complexes are utilized to catalyze a broad variety of reactions, including examples involving radicals. For such reactions, organic halides are by far the most versatile and attractive substrates. Our contributions to the catalysis of radical reactions from organic halides with copper complexes are summarized in this account.
1 Introduction
2 Copper-Catalyzed Radical Cross-Coupling Reactions
3 Copper-Catalyzed Radical Reactions
4 Copper-Catalyzed Radical Carbonylative Cross-Coupling Reactions
5 Photoinduced, Copper-Catalyzed Radical Reactions
6 Conclusions and Outlook
Key words
copper catalysis -
organic halides -
cross-coupling -
radical reactions -
copper complexes -
photoredox catalysis
Publication History
Received: 04 May 2023
© 2023. Thieme. All rights reserved
Georg Thieme Verlag KG
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