Synlett 2023; 34(17): 2001-2004
DOI: 10.1055/a-2131-3157
letter

Ni-Catalyzed Reductive Coupling of Alkyl Carbonochloridates and Aryl Iodides

Chonghuo Liu
,
Ken Yao
,
Yunrong Chen
We thank the National Natural Science Foundation of China (21901162) for financial support.


Abstract

A Ni-catalyzed reductive coupling of alkyl carbonochloridates and aryl iodides for the synthesis of aromatic esters has been developed. The present method is a new type of reductive coupling for building Csp2–CO bonds, and it avoids using toxic carbon monoxide gas. It tolerates various aryl iodides, and a coordinating group in alkyl carbonochloridates is key to improving the yield of the reaction.

Supporting Information



Publikationsverlauf

Eingereicht: 27. April 2023

Angenommen nach Revision: 17. Juli 2023

Accepted Manuscript online:
18. Juli 2023

Artikel online veröffentlicht:
14. September 2023

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