Thrombosis and Haemostasis, Table of Contents

CC BY-NC-ND 4.0 · Thromb Haemost 2023; 123(11): 1100-1104
DOI: 10.1055/a-2149-4431

Letter to the Editor

Short-Term Western Diet Causes Rapid and Lasting Alterations of Bone Marrow Physiology

Mariaelvy Bianchini

¹Helmholtz Zentrum München, Institute of Radiation Medicine, Neuherberg, Germany

²Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-Universität in Munich (LMU Munich), Munich, Germany

,

Zoe Möller-Ramon

²Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-Universität in Munich (LMU Munich), Munich, Germany

,

Christian Weber

²Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-Universität in Munich (LMU Munich), Munich, Germany

³German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany

⁴Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, Maastricht, The Netherlands

,

Remco T. A. Megens‡^*

²Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-Universität in Munich (LMU Munich), Munich, Germany

³German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany

⁴Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, Maastricht, The Netherlands

,

Johan Duchêne‡^*

²Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-Universität in Munich (LMU Munich), Munich, Germany

³German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany

› Author Affiliations

References
1 Libby P, Buring JE, Badimon L. et al. Atherosclerosis. Nat Rev Dis Primers 2019; 5 (01) 56
2 Rohde D, Vandoorne K, Lee IH. et al. Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease. Nat Cardiovasc Res 2022; 1 (01) 28-44
3 Morrison SJ, Scadden DT. The bone marrow niche for haematopoietic stem cells. Nature 2014; 505 (7483) 327-334
4 Pinho S, Frenette PS. Haematopoietic stem cell activity and interactions with the niche. Nat Rev Mol Cell Biol 2019; 20 (05) 303-320
5 Baccin C, Al-Sabah J, Velten L. et al. Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization. Nat Cell Biol 2020; 22 (01) 38-48
6 Gomariz A, Helbling PM, Isringhausen S. et al. Quantitative spatial analysis of haematopoiesis-regulating stromal cells in the bone marrow microenvironment by 3D microscopy. Nat Commun 2018; 9 (01) 2532
7 Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005; 121 (07) 1109-1121
8 Duchene J, Novitzky-Basso I, Thiriot A. et al. Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis. Nat Immunol 2017; 18 (07) 753-761
9 Pietras EM, Reynaud D, Kang YA. et al. Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions. Cell Stem Cell 2015; 17 (01) 35-46
10 Pelus LM, Fukuda S. Peripheral blood stem cell mobilization: the CXCR2 ligand GRObeta rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties. Exp Hematol 2006; 34 (08) 1010-1020
11 Serbina NV, Pamer EG. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol 2006; 7 (03) 311-317
12 Zink F, Stacey SN, Norddahl GL. et al. Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly. Blood 2017; 130 (06) 742-752
13 Jaiswal S, Natarajan P, Silver AJ. et al. Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease. N Engl J Med 2017; 377 (02) 111-121
14 Heyde A, Rohde D, McAlpine CS. et al. Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis. Cell 2021; 184 (05) 1348.e22-1361.e22
15 Young AL, Challen GA, Birmann BM, Druley TE. Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults. Nat Commun 2016; 7: 12484
16 Itkin T, Gur-Cohen S, Spencer JA. et al. Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature 2016; 532 (7599) 323-328
17 Kusumbe AP, Ramasamy SK, Itkin T. et al. Age-dependent modulation of vascular niches for haematopoietic stem cells. Nature 2016; 532 (7599) 380-384
18 Kunisaki Y, Bruns I, Scheiermann C. et al. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature 2013; 502 (7473) 637-643
19 Xu C, Gao X, Wei Q. et al. Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nat Commun 2018; 9 (01) 2449
20 Acar M, Kocherlakota KS, Murphy MM. et al. Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal. Nature 2015; 526 (7571) 126-130
21 Chen JY, Miyanishi M, Wang SK. et al. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche. Nature 2016; 530 (7589) 223-227
22 Yousif LF, Di Russo J, Sorokin L. Laminin isoforms in endothelial and perivascular basement membranes. Cell Adhes Migr 2013; 7 (01) 101-110
23 Gu YC, Kortesmaa J, Tryggvason K. et al. Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells. Blood 2003; 101 (03) 877-885
24 Susek KH, Korpos E, Huppert J. et al. Bone marrow laminins influence hematopoietic stem and progenitor cell cycling and homing to the bone marrow. Matrix Biol 2018; 67: 47-62
25 Mouw JK, Ou G, Weaver VM. Extracellular matrix assembly: a multiscale deconstruction. Nat Rev Mol Cell Biol 2014; 15 (12) 771-785
26 Christ A, Günther P, Lauterbach MAR. et al. Western diet triggers NLRP3-dependent innate immune reprogramming. Cell 2018; 172 (1–2): 162-175.e14

Supplementary Material

Supplementary Material

Supplementary Material