PDF herunterladen
Erfahrungsheilkunde 2023; 72(05): 277-285
DOI: 10.1055/a-2150-5556
Praxis

Evidenz- und erfahrungsbasierte Phytotherapie bei Erkrankungen der Haut

Peter W. Gündling
› Weitere Informationen
    Lizenzen und Reprints

Zusammenfassung

Im Gegensatz zu chemisch definierten Substanzen und Arzneimitteln sind Phytotherapeutika und Phytopharmaka Vielstoffgemische, die von der Natur über Jahrmillionen im Einklang mit ihrer Umwelt hervorgebracht wurden. Ihre Inhaltsstoffe dienen somit nicht nur dem Schutz und Gedeihen der Pflanzen selbst, sondern auch dem anderer Lebewesen und Lebensbereiche. Menschen und Tiere haben diese Eigenschaften schon früh wahrgenommen und seit Tausenden von Jahren genutzt. Wesentlicher Vorteil – bei richtiger Anwendung – dieser Vielstoffgemische ist ihre milde und breite Wirksamkeit und dadurch auch gute Verträglichkeit. Als Grenz- und Multifunktionsorgan bedarf die Haut – vielleicht mehr noch als andere Organe – einer ganzheitlichen Betrachtung. Somit sind bei deren Funktionsstörungen und Erkrankung alle Säulen der klassischen Naturheilverfahren von Bedeutung, insbesondere auch die Phytotherapie. Einige neuere und bewährte Erkenntnisse dazu werden nachfolgend anhand dreier klassischer Hautkrankheiten vorgestellt.

Abstract

In contrast to chemically defined substances and drugs, phytotherapeutics and phytopharmaceuticals are multicomponent mixtures that have been produced by nature over millions of years in harmony with the environment. Their ingredients are not only used for their own protection and flourishing, but also for that of other living creatures and areas of life. Humans and animals noticed these properties early on and have used them for thousands of years. The main advantage of these multicomponent mixtures – when used correctly – is their mild and broad effectiveness and thus also good tolerability. As border and multifunctional organ, the skin requires a holistic approach – perhaps even more than other organs. Thus, in the case of dysfunction and disease of the skin, all pillars of classical naturopathic medicine are important, especially phytotherapy. Some recent and proven findings in this regard are presented below on the basis of three classic skin diseases.

Schlüsselwörter

Phytotherapie - Hautkrankheiten - Akne vulgaris - Neurodermitis - Psoriasis vulgaris

Key words

phytotherapy - skin diseases - acne vulgaris - neurodermatitis - psoriasis vulgaris


Publikationsverlauf

Artikel online veröffentlicht:
10. Oktober 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • Literatur

  • 1 Antiga E, Bonciolini V, Volpi W. et al. Oral curcumin (meriva) is effective as an adjuvant treatment and is able to reduce IL-22 serum levels in patients with psoriasis vulgaris. Bio Med Res Int 2015; DOI: 10.1155/2015/283634.
    CrossrefPubMedGoogle Scholar
  • 2 Barbalho SM, de Sousa Gonzaga HF, de Souza GA. et al. Dermatological effects of curcuma species: A systematic review. Clin Exp Dermatol 2021; 46 (5) 825-833
    CrossrefPubMedGoogle Scholar
  • 3 Becker-Weimann SY, Ochsendorf FR. Akne in verschiedenen Lebensphasen: Ähnliche Klinik, unterschiedliche Konsequenzen. Kinder Jugendmed 2019; 19 (04) 241-246
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 4 Bernstein S, Donsky H, Hamilton GW. et al. Treatment of mild to moderate psoriasis with reliéva, a mahonia aquifolium extract – A double-blind, placebo-controlled study. Am J Ther 2006; 13 (2) 121-126
    CrossrefPubMedGoogle Scholar
  • 5 El Mihyaoui A, Esteves da Silva JCG, Charfi S. et al. Chamomile (matricaria chamomilla L.): A review of ethnomedicinal use, phytochemistry and pharmacological uses. Life (Basel) 2022; 12 (4) 479
    PubMedGoogle Scholar
  • 6 Elangovan A, Ramachandran J, Lakshmanan DK. et al. Ethnomedical, phytochemical and pharmacological insights on an Indian medicinal plant: The balloon vine (cardiospermum halicacabum Linn.). J Ethnopharmacol 2022; 291: 115143
    CrossrefPubMedGoogle Scholar
  • 7 Elsaie ML, Abdelhamid MF, Elsaaiee LT. et al. The efficacy of topical 2 % green tea lotion in mild-to-moderate acne vulgaris. J Drugs Dermatol 2009; 8 (4) 358-364
    PubMedGoogle Scholar
  • 8 European Medicines Agency Committee on Herbal Medicinal Products (HMPC). Assessment report on hamamelis virginiana L., cortex; hamamelis virginiana L., folium; hamamelis virginiana L., folium et cortex aut ramunculus destillatum, EMA/HMPC/114585/2008. Im Internet: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2010/04/WC500089242.pdf ; Stand: 22.08.2023
    PubMedGoogle Scholar
  • 9 Gamret AC, Price A, Fertig RM. et al. Complementary and alternative medicine therapies for psoriasis: A systematic review. JAMA Dermatol 2018; 154 (11) 1330-1337
    CrossrefPubMedGoogle Scholar
  • 10 Gendrisch F, Haarhaus B, Krieger N. et al. The effect of herbal medicinal products on psoriasis-like keratinocytes. Biomolecules 2021; 11 (3) 371
    CrossrefPubMedGoogle Scholar
  • 11 Gündling PW. Einsatzmöglichkeiten der Phytotherapie bei Hautkrankheiten. Schweiz Z Ganzheitsmed 2017; 29: 208-213
    CrossrefPubMedGoogle Scholar
  • 12 Gündling PW. Ganzheitliche Behandlung der Neurodermitis. Naturheilkunde 2016; 93 (1) 12-16
    PubMedGoogle Scholar
  • 13 Heinrich U, Tronnier H. Johanniskraut-Extrakt zur Pflege der atopischen Haut. Kosmet Med 2003; 24: 3-4
    PubMedGoogle Scholar
  • 14 Hellinger R, Koehbach J, Fedchuk H. et al. Immunosuppressive activity of an aqueous viola tricolor herbal extract. J Ethnopharmacol 2014; 151 (1) 299-306
    CrossrefPubMedGoogle Scholar
  • 15 Khoshkam Z, Zarrabi M, Sepehrizade Z. et al. The study of antimicrobial activities of partially purified cyclotide content and crude extracts from viola tricolor. J Med Bacteriol 2016; 5 (1/2) 29-35
    PubMedGoogle Scholar
  • 16 Lin Y-K, Chang C-J, Chang Y-C. et al. Clinical assessment of patients with recalcitrant psoriasis in a randomized, observer-blind, vehicle-controlled trial using indigo naturalis. Arch Dermatol 2008; 144: 1457-1464
    CrossrefPubMedGoogle Scholar
  • 17 Lin Y-K, See L-C, Huang Y-H. et al. Comparison of indirubin concentrations in Indigo naturalis ointment for psoriasis treatment: A randomized, double-blind, dosage-controlled trial. Br J Dermatol 2018; 178 (1) 124-131
    CrossrefPubMedGoogle Scholar
  • 18 Lin Y-K, Chang S-H, Yang C-Y. et al. Efficacy and safety of indigo naturalis ointment in treating atopic dermatitis: A randomized clinical trial. J Ethnopharmacol 2020; 250: 112477
    CrossrefPubMedGoogle Scholar
  • 19 Miraj S, Alesaeidi S. A systematic review study of therapeutic effects of matricaria recutita chamomile (chamomile). Electron Physician 2016; 8 (9) 3024-3031
    CrossrefPubMedGoogle Scholar
  • 20 Muhammed M, Nagabhushanam K, Sankarab N. et al. Clinical evaluation of AKBBA in the management of psoriasis. Clin Dermatol 2014; 2: 17-24
    PubMedGoogle Scholar
  • 21 Nardo VD, Gianfaldoni S, Tchernev G. et al. Use of curcumin in psoriasis. Open Access Maced J Med Sci 2018; 6: 218-220
    CrossrefPubMedGoogle Scholar
  • 22 Piazza S, Martinelli G, Vrhovsek U. et al. Anti-inflammatory and anti-acne effects of hamamelis virginiana bark in human keratinocytes. Antioxidants (Basel) 2022; 11 (6) 1119
    CrossrefPubMedGoogle Scholar
  • 23 Piazza S, Martinelli G, Magnavacca A. et al. Unveiling the ability of witch hazel (hamamelis virginiana l.) bark extract to impair keratinocyte inflammatory cascade typical of atopic eczema. Int J Mol Sci 2022; 23 (16) 9279
    CrossrefPubMedGoogle Scholar
  • 24 Seiwerth J, Tasiopoulou G, Hoffmann J. et al. Anti-inflammatory effect of a novel topical herbal composition (vel-091604) consisting of gentian root, licorice root and willow bark extract. Planta Med 2019; 85 (7) 608-614
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 25 Siddiqui MZ. Boswellia serrata, a potential antiinflammatory agent: An overview. Indian J Pharm Sci 2011; 73 (3) 255-261
    PubMedGoogle Scholar
  • 26 Soleimani V, Sahebkar A, Hosseinzadeh H. Turmeric (curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review. Phytother Res 2018; 32 (6) 985-995
    CrossrefPubMedGoogle Scholar
  • 27 Steinka I, Stankiewicz J, Kukułowicz A. et al. Influence of tagetes patula and viola tricolor on survival of staphylococcus aureus ATCC 25923. Heliyon 2022; 8 (11) e11777
    CrossrefPubMedGoogle Scholar
  • 28 Vaughn AR, Branum A, Sivamani RK. Effects of turmeric (curcuma longa) on skin health: A systematic review of the clinical evidence. Phytother Res 2016; 30 (8) 1243-1264
    CrossrefPubMedGoogle Scholar
  • 29 Weber N, Biehler K, Schwabe K. et al. Hop extract acts as an antioxidant with antimicrobial effects against propionibacterium acnes and staphylococcus aureus. Molecules 2019; 24 (2) 223
    CrossrefPubMedGoogle Scholar
  • 30 Werfel T, Aberer W, Ahrens F. et al. Leitlinie Neurodermitis (atopisches Ekzem; atopische Dermatitis). J German Soc Dermatol 2016; DOI: 10.1111/ddg.12884.
    CrossrefPubMedGoogle Scholar
  • 31 Wichtl M. Teedrogen und Phytopharmaka. Stuttgart: Wissenschaftliche Verlagsgesellschaft; 2016
    Google Scholar
  • 32 Wölfle U, Seelinger G, Schempp CM. Topical application of St. John’s wort (hypericum perforatum). Planta Med 2014; 80: 109-120
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 33 Wölfle U, Haarhaus B, Seiwerth J. et al. The herbal bitter drug gentiana lutea modulates lipid synthesis in human keratinocytes in vitro and in vivo. Int J Mol Sci 2017; 18 (8) 1814
    CrossrefPubMedGoogle Scholar
  • 34 Wölfle U, Hoffmann J, Schempp C. Die Möglichkeiten der Phytotherapie bei entzündlichen Hautkrankheiten. Z Phytother 2023; 44: 52-60
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 35 Yang R, Wang L, Yuan B. et al. The pharmacological activities of licorice. Planta Med 2015; 81 (18) 1654-1669
    Artikel in Thieme ConnectPubMedGoogle Scholar