Subscribe to RSS
DOI: 10.1055/a-2230-7372
Insulated tip/needle-knife endoscopic stricturotomy is safe and effective for treatment of non-traversable anorectal strictures
Abstract
Background and study aims The treatment of anorectal strictures is particularly challenging and historically focused on surgical resection and/or diversion. There are a number of endoscopic options, but repeat interventions are common. The use of the needle knife stricturotomy technique as an alternative to surgery in the treatment of a variety of strictures has been described, but its use for the treatment of severe anorectal and anopouch strictures has not been studied.
Patients and methods Our Inflammatory Bowel Disease department’s records were queried to identify patients with endoscopic non-traversable anorectal/anopouch strictures. Consecutive patients that underwent insulated tip/needle-knife endoscopic stricturotomy treatment were included. Primary outcome was immediate traversability of the treated stricture by the endoscope. Other outcomes included need for reintervention, 30-day post-procedure events, and follow-up period events.
Results All strictures were immediately successfully traversed following endoscopic stricturotomy treatment. The mean time to endoscopic reintervention was 5.3 months, with the majority of these patients undergoing repeat stricturotomy. Over a mean follow-up period of 12.8 months, two patients (8%) required surgical intervention (resection with coloanal anastomosis with a colostomy and complete proctectomy) for refractory stricture disease following initial endoscopic stricturotomy. Seven patients (29%) in our study have not required any further reintervention throughout the study period. There were no 30-day post-procedure adverse events and no adverse post-procedure events.
Conclusions Endoscopic stricturotomy is safe and effective in treating severe anorectal/anopouch strictures.
Publication History
Received: 22 January 2023
Accepted after revision: 24 October 2023
Article published online:
15 February 2024
© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Linares L, Moreira LF, Andrews H. et al. Natural history and treatment of anorectal strictures complicating Crohnʼs disease. Br J Surg 1988; 75: 653-655
- 2 Rieder F, Zimmermann EM, Remzi FH. et al. Crohnʼs disease complicated by strictures: a systematic review. Gut 2013; 62: 1072-1084
- 3 Jumbi T, Kuria K, Osawa F. et al. The effectiveness of digital anal dilatation in preventing anal strictures after anorectal malformation repair. J Pediatr Surg 2019; 54: 2178-2181
- 4 Singh VV, Draganov P, Valentine J. Efficacy and safety of endoscopic balloon dilation of symptomatic upper and lower gastrointestinal Crohnʼs disease strictures. J Clin Gastroenterol 2005; 39: 284-290
- 5 Werre A, Mulder C, van Heteren C. et al. Dilation of benign strictures following low anterior resection using Savary-Gilliard bougies. Endoscopy 2000; 32: 385-388
- 6 Suzuki N, Saunders BP, Thomas-Gibson S. et al. Colorectal stenting for malignant and benign disease: outcomes in colorectal stenting. Dis Colon Rectum 2004; 47: 1201-1207
- 7 Lavy A. Triamcinolone improves outcome in Crohnʼs disease strictures. Dis Colon Rectum 1997; 40: 184-186
- 8 Shen B, Fazio VW, Remzi FH. et al. Endoscopic balloon dilation of ileal pouch strictures. Am J Gastroenterol 2004; 99: 2340-2347
- 9 Lan N, Shen B. Endoscopic stricturotomy versus balloon dilation in the treatment of anastomotic strictures in Crohnʼs disease. Inflamm Bowel Dis 2018; 24: 897-907
- 10 Lian L, Stocchi L, Remzi FH. et al. Comparison of endoscopic dilation vs surgery for anastomotic stricture in patients with Crohnʼs disease following ileocolonic resection. Clin Gastroenterol Hepatol 2017; 15: 1226-1231
- 11 Mueller T, Rieder B, Bechtner G. et al. The response of Crohnʼs strictures to endoscopic balloon dilation. Aliment Pharmacol Ther 2010; 31: 634-639
- 12 Truong S, Willis S, Schumpelick V. Endoscopic therapy of benign anastomotic strictures of the colorectum by electroincision and balloon dilatation. Endoscopy 1997; 29: 845-849
- 13 Chon HK, Shin IS, Kim SW. et al. High grade anorectal stricture complicating Crohnʼs disease: endoscopic treatment using insulated-tip knife. Intest Res 2016; 14: 285-288
- 14 Shen B, Lian L, Kiran RP. et al. Efficacy and safety of endoscopic treatment of ileal pouch strictures. Inflamm Bowel Dis 2011; 17: 2527-2535
- 15 Lan N, Shen B. Endoscopic stricturotomy with needle knife in the treatment of strictures from inflammatory bowel disease. Inflamm Bowel Dis 2017; 23: 502-513
- 16 Lan N, Wu JJ, Wu XR. et al. Endoscopic treatment of pouch inlet and afferent limb strictures: stricturotomy vs. balloon dilation. Surg Endoscopy 2021; 35: 1722-1733
- 17 Lan N, Stocchi L, Delaney CP. et al. Endoscopic stricturotomy versus ileocolonic resection in the treatment of ileocolonic anastomotic strictures in Crohnʼs disease. Gastrointest Endoscopy 2019; 90: 259-268
- 18 Shen B, Kochhar G, Navaneethan U. et al. Practical guidelines on endoscopic treatment for Crohnʼs disease strictures: a consensus statement from the Global Interventional Inflammatory Bowel Disease Group. Lancet Gastroenterol Hepatol 2020; 5: 393-405
- 19 Keighley MR, Allan RN. Current status and influence of operation on perianal Crohnʼs disease. Int J Colorectal Dis 1986; 1: 104-107
- 20 Lightner AL, Click B, Yamamoto T. et al. Management of isolated anal strictures in Crohnʼs disease. Dis Colon Rectum 2020; 63: 1639-1647
- 21 Shen B, Kochhar G, Navaneethan U. et al. Role of interventional inflammatory bowel disease in the era of biologic therapy: a position statement from the Global Interventional IBD Group. Gastrointest Endosc 2019; 89: 215-237
- 22 Loras C, Andújar X, Gornals JB. et al. Self-expandable metal stents versus endoscopic balloon dilation for the treatment of strictures in Crohnʼs disease (ProtDilat study): an open-label, multicentre, randomised trial. Lancet Gastroenterol Hepatol 2022; 7: 332-341
- 23 Navaneethan U, Lourdusamy V, Njei B. et al. Endoscopic balloon dilation in the management of strictures in Crohnʼs disease: a systematic review and meta-analysis of non-randomized trials. Surg Endosc 2016; 30: 5434-5443