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Pneumologie 2024; 78(06): 420-426
DOI: 10.1055/a-2295-5921
Schritt für Schritt

EBUS-gestützte Kryobiopsie mediastinaler Läsionen – Schritt für Schritt

EBUS-guided cryobiopsy in the diagnosis of mediastinal lesions – step by step
Erik Büscher
,
Ruediger Karpf-Wissel 
,
Faustina Funke
,
Kaid Darwiche
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Die endobronchiale ultraschallgestützte Kryobiopsie (EBUS-KB) ermöglicht die Gewinnung großer Proben mit intakter Gewebearchitektur. Dies ist z.B. für die Lymphomdiagnostik oder für molekularpathologische Untersuchungen zur personalisierten Therapie des Lungenkarzinoms von essentieller Bedeutung. Die Sicherheit und Effektivität der EBUS-KB hängt entscheidend von einer präzisen Durchführung und einer strengen Indikationsstellung ab. Im Folgenden wird die Vorgehensweise erläutert, wie sie in der Ruhrlandklinik praktiziert wird.

Abstract

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the gold standard in the diagnosis of mediastinal and hilar lesions. For certain purposes, such as the diagnosis and subtyping of lymphoproliferative disorders or molecular pathology, a larger amount of intact sample material is required. EBUS cryobiopsy is a new and efficient tool for this purpose. As it is a new approach, there is still no standardised workflow. In this review, we present the procedure step by step as it is performed at the Ruhrlandklinik in Essen.

Schlüsselwörter

EBUS-Kryobiopsie - mediastinale Läsionen - Schritt für Schritt

Keywords

EBUS-guided cryobiopsy - mediastinal lesions - step by step


Publication History

Received: 24 November 2023

Accepted after revision: 26 March 2024

Article published online:
12 June 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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