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DOI: 10.1055/a-2295-5921
EBUS-gestützte Kryobiopsie mediastinaler Läsionen – Schritt für Schritt
EBUS-guided cryobiopsy in the diagnosis of mediastinal lesions – step by step
Die endobronchiale ultraschallgestützte Kryobiopsie (EBUS-KB) ermöglicht die Gewinnung großer Proben mit intakter Gewebearchitektur. Dies ist z.B. für die Lymphomdiagnostik oder für molekularpathologische Untersuchungen zur personalisierten Therapie des Lungenkarzinoms von essentieller Bedeutung. Die Sicherheit und Effektivität der EBUS-KB hängt entscheidend von einer präzisen Durchführung und einer strengen Indikationsstellung ab. Im Folgenden wird die Vorgehensweise erläutert, wie sie in der Ruhrlandklinik praktiziert wird.
Abstract
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the gold standard in the diagnosis of mediastinal and hilar lesions. For certain purposes, such as the diagnosis and subtyping of lymphoproliferative disorders or molecular pathology, a larger amount of intact sample material is required. EBUS cryobiopsy is a new and efficient tool for this purpose. As it is a new approach, there is still no standardised workflow. In this review, we present the procedure step by step as it is performed at the Ruhrlandklinik in Essen.
Publication History
Received: 24 November 2023
Accepted after revision: 26 March 2024
Article published online:
12 June 2024
© 2024. Thieme. All rights reserved.
Georg Thieme Verlag KG
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