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Arthritis und Rheuma 2024; 44(04): 268-275
DOI: 10.1055/a-2329-8510
Kinderrheumatologie
Übersichtsartikel

Die IgA(Purpura Schönlein-Henoch)-Vaskulitis

Anton Hospach
1   Zentrum für Pädiatrische Rheumatologie am Klinikum Stuttgart (ZEPRAS), Stuttgart
,
Dominik Müller
2   Klinik für Pädiatrie m. S. Gastroenterologie, Nephrologie und Stoffwechselmedizin, Charité, Universitätsmedizin, Berlin
,
Martin Pohl
3   Sektion Kindernephrologie, Zentrum für Kinder- und Jugendmedizin, Universitätsklinikum Freiburg, Freiburg
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ZUSAMMENFASSUNG

Die IgA-Vaskulitis (früher Purpura Schönlein-Henoch) ist eine systemische, immunkomplexvermittelte Vaskulitis der kleinen Gefäße, die gekennzeichnet ist durch die klinische Trias aus palpabler Purpura, Bauch- und Gelenkschmerzen. Es ist die häufigste Vaskulitis im Kindes- und Jugendalter. Die Diagnose ist klinisch zu stellen. Die kutane Vaskulitis zeigt überwiegend eine Spontanremission. Die Nieren sind häufig und in unterschiedlichem Ausmaß betroffen. Bei schweren Verläufen können ein akutes Nierenversagen und ein nephrotisches Syndrom auftreten sowie renale Langzeitschäden verbleiben.

Schlüsselwörter

IgA-Vaskulitis - Diagnostik - IgA-Vaskulitis - Steroide - Vaskulitis-Klassifikation - IgA-Nephritis - Haut-Vaskulitis


Publication History

Article published online:
06 September 2024

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