Virusinfektionen und Typ-1-Diabetes: neue diagnostische und therapeutische Ansätze

Typ-1-Diabetes, der aus der autoimmunen Zerstörung von β-Zellen resultiert, ist eine schwere Krankheit, nicht nur wegen der belastenden Spätkomplikationen, die zu einer verkürzten Lebenserwartung führen, sondern auch aufgrund der hohen täglichen Belastung, die durch die Anforderungen der Insulintherapie auf die Patienten und ihre Familien ausgeübt wird. Trotz intensiver biochemischer, immunologischer, epidemiologischer und klinischer Forschung in den letzten 100 Jahren ist die Ätiologie von Typ-1-Diabetes weitgehend noch nicht geklärt. Es scheint das Ergebnis eines komplexen Zusammenspiels zwischen genetischer Veranlagung, dem Immunsystem und Umweltfaktoren zu sein.

Publication History

Article published online:
09 October 2024

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