Facile Synthesis of 2- and 3-Substituted Indoles Using a Catalytic Amount of Pd/C and 1-Octene System

Abstract

A novel and efficient synthesis of 3- and 2-substituted indoles starting from 2-(2-nitro-1-phenylethyl or 2-nitro-1-alkyl)cyclohexanones and 1,4-diketones, respectively, using a catalytic amount of Pd/C and 1-octene system is reported.

Key words

2- and 3- substituted indoles - Pd/C - 1-octene - one-pot synthesis - nitrone - 5-keto nitroalkanes - 1,4-diketone - ammonium acetate

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