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CC BY-NC-ND 4.0 · Endosc Int Open 2025; 13: a24657130
DOI: 10.1055/a-2465-7130
Original article

Feasibility of a novel 5F plastic stent in endoscopic transpapillary gallbladder drainage for acute cholecystitis

Kazunari Nakahara 
1   Department of Gastroenterology, St. Marianna University School of Medicine, Kawasaki, Japan
,
Yosuke Igarashi
1   Department of Gastroenterology, St. Marianna University School of Medicine, Kawasaki, Japan
,
Akihiro Sekine
1   Department of Gastroenterology, St. Marianna University School of Medicine, Kawasaki, Japan
,
Yusuke Satta
1   Department of Gastroenterology, St. Marianna University School of Medicine, Kawasaki, Japan
,
Haruka Niwa
1   Department of Gastroenterology, St. Marianna University School of Medicine, Kawasaki, Japan
,
Junya Sato
1   Department of Gastroenterology, St. Marianna University School of Medicine, Kawasaki, Japan
,
Shinjiro Kobayashi
2   Department of Gastroenterogical and General Surgery, St. Marianna University School of Medicine, Kawasaki, Japan
,
Takehito Otsubo
2   Department of Gastroenterogical and General Surgery, St. Marianna University School of Medicine, Kawasaki, Japan
,
Keisuke Tateishi
1   Department of Gastroenterology, St. Marianna University School of Medicine, Kawasaki, Japan
› Author AffiliationsSupported by: JSPS KAKENHI 23K07405
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Abstract

Background and study aims

Many reports have demonstrated the efficacy of endoscopic transpapillary gallbladder stenting (EGBS) for acute cholecystitis (AC), most of which have traditionally used a 7F plastic stent. The study aim was to evaluate the efficacy of a novel 5F plastic stent in EGBS for AC.

Patients and methods

We designed a retrospective study that compared the outcomes between 7F and 5F stents in patients undergoing EGBS. Among 147 patients who underwent endoscopic transpapillary gallbladder drainage for AC between January 2019 and July 2023, 104 who underwent EGBS using a 7F (n = 53) or 5F (n = 51) plastic stent were included in the analysis.

Results

The technical success rate for EGBS, clinical success rate for AC, and early adverse events (AEs) rate in the 7F and 5F groups were 92.5% vs 100%, 100% vs 98.0%, and 5.7% vs 3.9%, respectively, with no significant differences. However, only in the 7F group, four patients failed stent insertion and three patients developed postprocedure pancreatitis. Furthermore, incidence of hyperamylasemia was lower in the 5F group (24.5% vs 9.8%, P = 0.047). The late AE rate did not differ significantly between the 7F and 5F groups (14.3% vs 10.0%). The median time to late AE was 238 days for the 7F group and 187 days for the 5F group, with no significant difference.

Conclusions

A 5F stent can provide outcomes comparable to those of a 7F stent and help prevent hyperamylasemia.

Keywords

Pancreatobiliary (ERCP/PTCD) - Stones - ERC topics


Publication History

Received: 05 August 2024

Accepted after revision: 07 November 2024

Accepted Manuscript online:
11 November 2024

Article published online:
07 January 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Georg Thieme Verlag KG
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Bibliographical Record
Kazunari Nakahara, Yosuke Igarashi, Akihiro Sekine, Yusuke Satta, Haruka Niwa, Junya Sato, Shinjiro Kobayashi, Takehito Otsubo, Keisuke Tateishi. Feasibility of a novel 5F plastic stent in endoscopic transpapillary gallbladder drainage for acute cholecystitis. Endosc Int Open 2025; 13: a24657130.
DOI: 10.1055/a-2465-7130
 

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