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Diabetologie und Stoffwechsel 2025; 20(01): 47-58
DOI: 10.1055/a-2481-2004
Leitlinie

Kurzfassung der KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease (Leitlinie für die klinische Praxis zur Diabetesbehandlung bei chronischer Nierenkrankheit): eine Aktualisierung auf Grundlage neuer Erkenntnisse

Executive Summary of the KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease: An Update Based on New Evidence
Peter Rossing
1   Steno Diabetes Center Copenhagen, Kopenhagen, Dänemark
2   Universität Kopenhagen, Kopenhagen, Dänemark
,
M. L. Caramori
3   Division of Diabetes, Endocrinology and Metabolism, University of Minnesota, Minneapolis, Minnesota, USA
,
Juliana C.N. Chan
4   Department of Medicine and Therapeutics, Hong Kong Institute of Diabetes and Obesity, Hong Kong, China
5   Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong, China
,
Hiddo J.L. Heerspink
6   Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Niederlande
,
Clint Hurst
7   Houston, Texas, USA
,
Kamlesh Khunti
8   Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK
,
Adrian Liew
9   The Kidney & Transplant Practice, Mount Elizabeth Novena Hospital, Singapur
,
Erin D. Michos
10   Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
,
Sankar D. Navaneethan
11   Section of Nephrology, Department of Medicine, Selzman Institute for Kidney Health, Baylor College of Medicine, Houston, Texas, USA
12   Section of Nephrology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
,
Wasiu A. Olowu
13   Pediatric Nephrology and Hypertension Unit, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, State of Osun, Nigeria
,
Tami Sadusky
14   Seattle, Washington, USA
,
Nikhil Tandon
15   Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, Indien
,
Katherine R. Tuttle
16   Division of Nephrology, University of Washington, Spokane, Washington, USA
,
Christoph Wanner
17   Abteilung für Nephrologie, Universitätsklinikum Würzburg, Würzburg, Deutschland
,
Katy G. Wilkens
18   Nutrition and Fitness Services, Northwest Kidney Centers, Seattle, Washington, USA
,
Sophia Zoungas
19   School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australien
,
Jonathan C. Craig
20   College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australien
21   Cochrane Kidney and Transplant, Sydney, New South Wales, Australien
,
David J. Tunnicliffe
21   Cochrane Kidney and Transplant, Sydney, New South Wales, Australien
22   Sydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australien
,
Marcello A. Tonelli
23   Department of Medicine, University of Calgary, Calgary, Alberta, Kanada
,
Michael Cheung
24   KDIGO, Brüssel, Belgien
,
Amy Earley
24   KDIGO, Brüssel, Belgien
,
Ian H. de Boer
25   Kidney Research Institute, University of Washington, Seattle, Washington, USA
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Vorwort zur Übersetzung der KDIGO-Leitlinie Diabetes und CKDDiabetologie und Stoffwechsel 2025; 20(01): 45-46
DOI: 10.1055/a-2493-0919

Zusammenfassung

Die Kidney Disease: Improving Global Outcomes (KDIGO) 2022 Klinische Praxisrichtlinie für die Behandlung des Diabetes bei chronischer Nierenkrankheit (chronic kidney disease, CKD) stellt eine Aktualisierung der KDIGO-Leitlinie 2020 dar. Die Leitlinie richtet sich an eine breite Zielgruppe von Klinikern, die Menschen mit Diabetes und CKD behandeln. Zu den Themenbereichen, deren Empfehlungen auf der Grundlage neuer Erkenntnisse aktualisiert wurden, gehören die Kapitel 1: Umfassende Versorgung von Patienten mit Diabetes und CKD sowie Kapitel 4: Glukosesenkende Therapien bei Patienten mit Typ-2-Diabetes (T2 D) und CKD. Der Inhalt früherer Kapitel zur glykämischen Überwachung und zu den Zielen bei Patienten mit Diabetes und CKD (Kapitel 2), Lebensstilinterventionen bei Patienten mit Diabetes und CKD (Kapitel 3) und Ansätzen für das Management von Patienten mit Diabetes und CKD (Kapitel 5) werden als aktuell erachtet und wurden nicht geändert. Diese aktualisierte Leitlinie wurde nach einem eindeutigen Prozess der Evidenzprüfung und -bewertung entwickelt. Die Behandlungsansätze und Leitlinienempfehlungen basieren auf systematischen Übersichten relevanter Studien und Bewertung der Evidenz-Qualität. Die Stärke der Empfehlungen folgt dem GRADE-Ansatz (Grading of Recommendations Assessment, Development and Evaluation).

Die Grenzen der Evidenzen werden erörtert, und es werden Bereiche identifiziert, in denen zusätzliche Forschung erforderlich ist.

Abstract

The Kidney Disease: Improving Global Outcomes (KDIGO) 2022 Clinical Practice Guideline for the Management of Diabetes in Chronic Kidney Disease (CKD) is an update of the KDIGO 2020 guideline. The guideline is aimed at a broad audience of clinicians treating people with diabetes and CKD. Topics with recommendations updated based on new evidence include Chapter 1: Comprehensive Care in Patients with Diabetes and CKD, and Chapter 4: Glucose-Lowering Therapies in Patients with Type 2 Diabetes (T2 D) and CKD. The content of previous chapters on glycemic monitoring and targets in patients with diabetes and CKD (Chapter 2), lifestyle interventions in patients with diabetes and CKD (Chapter 3), and approaches to the management of patients with diabetes and CKD (Chapter 5) are considered current and have not been changed. This updated guideline was developed through a rigorous process of evidence review and evaluation. Treatment approaches and guideline recommendations are based on systematic reviews of relevant studies and assessment of evidence quality. The strength of the recommendations follows the GRADE approach (Grading of Recommendations Assessment, Development and Evaluation). The limitations of the evidence are discussed, and areas where additional research is needed are identified.

Schlüsselwörter

Angiotensin-Converting-Enzym-Inhibitor - Angiotensin-II-Rezeptor-Blocker - chronische Nierenkrankheit - Dialyse - Evidenzbasiert - GLP-1-Rezeptor-Agonist - Glykämie - glykämische Überwachung - glykämische Ziele - Leitlinie - HbA1c - Hämodialyse - KDIGO - Lebensstil - Metformin - Mineralokortikoid-Rezeptor-Antagonist - Versorgungsmodelle - Ernährung - Renin-Angiotensin-System - Selbstmanagement - SGLT2-Hemmer - systematische Überprüfung - teambasierte Versorgung

Keywords

Angiotensin-converting enzyme inhibitor - Angiotensin II receptor blocker - chronic kidney disease - dialysis - evidence-based - GLP-1 receptor agonist - Glycemia - glycemic monitoring - glycemic targets - guideline - HbA1c (hemoglobin A1c) - hemodialysis - KDIGO (Kidney Disease: Improving Global Outcomes) - lifestyle - metformin - mineralocorticoid receptor antagonist - care models - nutrition - renin-angiotensin system - self-management - SGLT2 inhibitor - systematic review - team-based care

* Zahlungen an die Institution.


Zusatzmaterial finden Sie unter https://www.kidney-international.org/article/S0085-2538(22)00518-X/fulltext



Publication History

Article published online:
27 January 2025

© 2025. Thieme. All rights reserved.

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

 

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