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CC BY 4.0 · Endosc Int Open
DOI: 10.1055/a-2788-3397
Original article

Adenoma detection rates and complications on colonoscopy in patients aged 75-79 years vs 70-74 years: A propensity-score matching study

Authors

  • Osamu Toyoshima 

    1   Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo, Japan

  • Toshihiro Nishizawa 

    2   Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University, School of Medicine, Tokyo, Japan

  • Shuntaro Yoshida

    3   Toyoshima Endoscopy Clinic, Setagaya, Japan (Ringgold ID: RIN577428)

  • Tomoharu Yamada

    4   Gastroenterology, Toyoshima　Endoscopy Clinic, Tokyo, Japan

  • Keisuke Mabuchi

    5   Department of Gastroenterology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan

  • Takuma Kaneko

    5   Department of Gastroenterology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan

  • Mari Mizutani 

    6   1) Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine Graduate School of Medicine, Shinjuku-ku, Japan (Ringgold ID: RIN38084)

  • Hirotoshi Ebinuma

    7   Gastroenterology, International University of Health and Welfare Mita Hospital, Minata-ku, Japan (Ringgold ID: RIN36767)

  • Mitsuhiro Fujishiro 

    8   Department of Endoscopy and Endoscopic Surgery, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan

  • Keisuke Hata

    1   Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo, Japan
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Background: Several guidelines recommend the discontinuation of routine surveillance colonoscopy after the age of 75 years. Since Japan has one of the longest life expectancies, we considered ceasing at the age of 80 years. We compared patients aged 75-79 years with those aged 70-74 years, regarding adenoma detection rate, the mean number of adenomas per colonoscopy, and adverse events. Methods: This propensity-score matching study included patients aged 70-79 with a performance status of 0-1 who underwent colonoscopies at Toyoshima Endoscopy Clinic between 2017 and 2024. Patients aged 75-79 years were matched with those aged 70-74 years for baseline characteristics using the propensity score. Adenoma detection rate, the mean number of adenomas per colonoscopy, frequency of respiratory depression, hypotension and delayed post-polypectomy bleeding were compared between the two groups. Results: During the study period, 3415 patients were included. The adenoma detection rate in patients aged 75-79 years was higher than that in patients aged 70-74 years (66.5% vs 62.2%, P = 0.021). The mean number of adenomas per colonoscopy in patients aged 75-79 years was higher than that in patients aged 70-74 years (1.54 vs 1.38, P = 0.014). The two groups did not show significant differences in respiratory depression (2.6% vs 2.3%), hypotension (0.8% vs 1.0%) or delayed post-polypectomy bleeding (0.2% vs 0.4%). Conclusion: Colonoscopies for patients aged 75-79 are safe and effective in Japan.



Publication History

Received: 07 March 2025

Accepted after revision: 14 January 2026

Accepted Manuscript online:
14 January 2026

© . The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

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Bibliographical Record
Osamu Toyoshima, Toshihiro Nishizawa, Shuntaro Yoshida, Tomoharu Yamada, Keisuke Mabuchi, Takuma Kaneko, Mari Mizutani, Hirotoshi Ebinuma, Mitsuhiro Fujishiro, Keisuke Hata. Adenoma detection rates and complications on colonoscopy in patients aged 75-79 years vs 70-74 years: A propensity-score matching study. Endosc Int Open ; 0: a27883397.
DOI: 10.1055/a-2788-3397