Effects of Altered Thyroid Function Upon Cortisol Secretion in Man

G. Copinschi; R. Leclercq; O. D. Bruno; A. Cornil

doi:10.1055/s-0028-1094119

Hormone and Metabolic Research, Inhaltsverzeichnis

Horm Metab Res 1971; 3(6): 437-442
DOI: 10.1055/s-0028-1094119

Originals

Effects of Altered Thyroid Function Upon Cortisol Secretion in Man

G. Copinschi , R. Leclercq , O. D. Bruno , A. Cornil

Clinique Médicale, Laboratoires de Médecine Expérimentale, de Chimie Clinique et-de Physiopathologie, Université Libre de Bruxelles, Bruxelles, Belgium

Abstract

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Abstract

The adrenocortical function was studied in adult patients with hyperthyroidism or with myxoedema. In 19 hyperthyroid women, the Cortisol secretion rate was significantly increased (30.6 ± 7.4 mg/d vs 17.8 ± 4.8 mg/d in normal controls); it was significantly decreased in 14 hypothyroid patients (13.7 ± 5.0 mg/d vs 20.5 ± 5.4 mg/d in matched controls). Changes in urinary excretion of Cortisol metabolites were more pronounced than in Cortisol secretion. Adrenocortical modifications were mostly reversible after recovery.

Key words

Cortisol Secretion in Hyperthyroidism - Cortisol Secretion in Hypothyroidism - Excretion of 17-Ketogenic Steroids in Hyperthyroidism - Excretion of 17-Ketogenic Steroids in Hypothyroidism

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