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Synlett 2010(3): 501-502  
DOI: 10.1055/s-0029-1219338
SPOTLIGHT
© Georg Thieme Verlag Stuttgart ˙ New York

Ethyl 2-Cyano-3,3-bis(methylthio)acrylate

Mohan Balasaheb Kalyankar*
Department of Organic Chemistry, North Maharashtra University, Jalgaon-425001, India
e-Mail: kalyankar.mb@rediffmail.com;
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Publikationsdatum:
25. Januar 2010 (online)

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Introduction

Ethyl 2-cyano-3,3-bis(methylthio)acrylate (Figure  [¹] ) was prepared by the reaction of ethyl cyanoacetate, carbon di­sulfide and dimethyl sufate in the presence of a base. [¹] Gommper and co-workers studied this reaction thoroughly. The electron-attracting groups on C2 makes it a very useful reagent for the preparation of heterocyclic compounds. [²] Moreover, Ethyl 2-cyano-3,3-bis(methyl­thio)acrylate can also be prepared efficiently using sodium ethoxide as a base. [³] In the literature numerous reports appeared highlighting its chemistry and use.

Figure 1 Ethyl 2-Cyano-3,3-bis(methylthio)acrylate