RSS-Feed abonnieren
DOI: 10.1055/s-0029-1236437
The Patient with Asymptomatic Shortened Cervix at 23 to 28 Weeks: Is Delivery Imminent?
Publikationsverlauf
Publikationsdatum:
14. August 2009 (online)

ABSTRACT
We investigated whether the presence of symptoms predicts the timing of subsequent spontaneous preterm birth in a cohort of women with cervical length (CL) <1.5 cm. A retrospective cohort study was conducted that included patients from 23 to 28 weeks' gestation with a CL <1.5 cm on routine ultrasound. Two groups were defined on the basis of presenting symptoms at the time of the ultrasound examination: asymptomatic patients and those with symptoms of preterm labor. The incidence of delivery within 2 weeks was determined for both groups. A total of 88 patients with CL <1.5 cm were identified from an ultrasound database. There were 52 patients with CL <1.5 cm and no symptoms. Of these, 1 (1.9%) delivered within 2 weeks. The remaining 36 patients had a CL <1.5 cm and symptoms of preterm labor. Of these, 11 (30.6%) delivered within 2 weeks (relative risk 15.9, 95% confidence interval 2.1 to 118). Premature cervical shortening at 23 to 28 weeks, in the absence of symptoms of preterm labor, is rarely associated with preterm delivery within 2 weeks. Following those patients clinically may prevent prolonged hospitalization and allow steroid administration closer to the date of delivery.
KEYWORDS
Prematurity - preterm birth - preterm labor - ultrasound - short cervix
REFERENCES
- 1 Institute of Medicine .Preterm Birth: Causes, Consequences, and Prevention. Washington, DC; National Academics Press 2006
- 2 Berkowitz G S, Blackmore-Prince C, Lapinski R H, Savitz D A. Risk factors for preterm birth subtypes. Epidemiology. 1998; 9 279-285
- 3 McElrath T F, Hecht J L, Dammann O ELGAN Study Investigators et al. Pregnancy disorders that lead to delivery before the 28th week of gestation: an epidemiologic approach to classification. Am J Epidemiol. 2008; 168 980-989
- 4 Mercer B M. Preterm premature rupture of the membranes. Obstet Gynecol. 2003; 101 178-193
- 5 Saigal S, Doyle L W. An overview of mortality and sequelae of preterm birth from infancy to adulthood. Lancet. 2008; 371 261-269
- 6 Heath V C, Southall T R, Souka A P, Elisseou A, Nicolaides K H. Cervical length at 23 weeks of gestation: prediction of spontaneous preterm delivery. Ultrasound Obstet Gynecol. 1998; 12 312-317
- 7 Goldenberg R L, Iams J D, Mercer B M National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network et al. What we have learned about the predictors of preterm birth. Semin Perinatol. 2003; 27 185-193
- 8 Fox N S, Jean-Pierre C, Predanic M, Chasen S T. Does hospitalization prevent preterm delivery in the patient with a short cervix?. Am J Perinatol. 2007; 24 49-53
- 9 Crowley P A. Antenatal corticosteroid therapy: a meta-analysis of the randomized trials, 1972 to 1994. Am J Obstet Gynecol. 1995; 173 322-335
- 10 Crowley P. Antenatal corticosteroids—current thinking. BJOG. 2003; 110(suppl 20) 77-78
- 11 Iams J D. Prediction and early detection of preterm labor. Obstet Gynecol. 2003; 101 402-412
- 12 Alfirevic Z. Cerclage: we all know how to do it but can't agree when to do it. Obstet Gynecol. 2006; 107(2 Pt 1) 219-220
- 13 Leitich H, Brunbauer M, Kaider A, Egarter C, Husslein P. Cervical length and dilatation of the internal cervical os detected by vaginal ultrasonography as markers for preterm delivery: a systematic review. Am J Obstet Gynecol. 1999; 181 1465-1472
- 14 Gomez R, Galasso M, Romero R et al.. Ultrasonographic examination of the uterine cervix is better than cervical digital examination as a predictor of the likelihood of premature delivery in patients with preterm labor and intact membranes. Am J Obstet Gynecol. 1994; 171 956-964
- 15 Iams J D, Goldenberg R L, Meis P J National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network et al. The length of the cervix and the risk of spontaneous premature delivery. N Engl J Med. 1996; 334 567-572
- 16 Gomez R, Romero R, Medina L et al.. Cervicovaginal fibronectin improves the prediction of preterm delivery based on sonographic cervical length in patients with preterm uterine contractions and intact membranes. Am J Obstet Gynecol. 2005; 192 350-359
- 17 Smith R. Parturition. N Engl J Med. 2007; 356 271-283
- 18 House M, Socrate S. The cervix as a biomechanical structure. Ultrasound Obstet Gynecol. 2006; 28 745-749
- 19 Stys S J, Clewell W H, Meschia G. Changes in cervical compliance at parturition independent of uterine activity. Am J Obstet Gynecol. 1978; 130 414-418
Fadi G MirzaM.D.
Clinical Fellow in Maternal-Fetal Medicine, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Medical Center
622 West 168th Street, New York, NY 10032
eMail: fgm2107@columbia.edu