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DOI: 10.1055/s-0029-1241872
© Georg Thieme Verlag KG Stuttgart · New York
Pulmonary Hypertensive Crisis Requiring ECMO Associated with Re-warming from whole Body Hypothermia for Hypoxic Ischemic Encephalopathy: Clinical Observations from a Case Series
Publikationsverlauf
Publikationsdatum:
28. Oktober 2009 (online)

Introduction
Hypothermia reduces the risk of death and/or disability in infants with moderate to severe hypoxic ischemic encephalopathy (HIE) [1]. Due to its apparent safety/efficacy, this technique is gaining in popularity. While pulmonary hypertension (PHTN) is a known potential risk associated with hypothermia (20–30%) [2], the associated frequency may be higher than previously described.
Our center routinely treats patients with moderate to severe HIE with hypothermia according to a previously published protocol [3]. Since December 2005, approximately 30 infants have been treated at our center. This communication describes our clinical observation of a higher than expected occurrence of severe pulmonary hypertensive crisis requiring extracorporeal membrane oxygenation (ECMO) associated with re-warming from whole body hypothermia.
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Correspondence
Dr. Charles S. Cox Jr
University of Texas Medical School at Houston
Department of Pediatric Surgery
6431 Fannin Street, MSB 5.236
Houston, TX 77030
United States
Telefon: +1713 500 7307
Fax: +1713 500 7296
eMail: charles.s.cox@uth.tmc.edu