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DOI: 10.1055/s-0029-1245168
© Georg Thieme Verlag KG Stuttgart · New York
Die Zukunft der invasiven Parkinson-Therapie
Parkinson’s Disease – the Future of Invasive TherapyPublikationsverlauf
Publikationsdatum:
01. März 2010 (online)
![](https://www.thieme-connect.de/media/fdn/2010S01/lookinside/thumbnails/10.1055-s-0029-1245168-1.jpg)
Zusammenfassung
Invasive Therapien haben in der Behandlung der Parkinson-Erkrankung eine lange Tradition. Während die tiefe Hirnstimulation bei fortgeschrittener Parkinson-Erkrankung mit Fluktuationen mittlerweile zu den etablierten Therapieverfahren zählt, sind für die Anwendung von Duodopa und Apomorphin noch Klasse I-Studien erforderlich. Die Transplantationen von fötalen Zellen und zukünftig vielleicht Stammzellen, und die Gentherapie gehören zu den zukünftig aussichtsreichen Interventionen.
Abstract
For the treatment of Parkinson’s disease invasive therapies have a long tradition. Deep brain stimulation is a well-established treatment option for the treatment of advanced Parkinson’s disease with fluctuations. Further promising interventions for invasive therapy of Parkinson’s disease are transplantation of foetal cells and stem cells, gene therapy and the use of duodopa and apomorhine.
Schlüsselwörter
invasive Therapien bei Parkinson - Transplantation - Gentherapie - tiefe Hirnstimulation
Keywords
invasive therapy by Parkinson’s disease - transplantation - gene therapy - deep brain stimulation
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Prof. Dr. Günther Deuschl
Neurologische Klinik, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel
Schittenhelmstr. 10
24105 Kiel
eMail: g.deuschl@neurologie.uni-kiel.de