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Planta Med 2010; 76(15): 1758-1761
DOI: 10.1055/s-0030-1249807
Natural Product Chemistry
Letters
© Georg Thieme Verlag KG Stuttgart · New York

Cucurbitane-Type Triterpenoids from Momordica charantia

Jun Ma1 , Paul Whittaker1 , Amy C. Keller2 , Eugene P. Mazzola1 , Rahul S. Pawar1 , Kevin D. White1 , John H. Callahan1 , Edward J. Kennelly2 , Alexander J. Krynitsky1 , Jeanne I. Rader1
  • 1Office of Regulatory Science, Center for Food Safety and Applied Nutrition, U. S. Food and Drug Administration, College Park, MD, USA
  • 2Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, Bronx, NY, USA
Further Information

Publication History

received January 15, 2010 revised March 5, 2010

accepted March 9, 2010

Publication Date:
08 April 2010 (online)

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Erratum for: Cucurbitane-Type Triterpenoids from Momordica charantiaPlanta Med 2012; 78(01): 102-102
DOI: 10.1055/s-0031-1280467

Abstract

One new cucurbitane-type triterpenoid glycoside, momordicoside X (1), together with five known cucurbitane-type triterpenoids and related glycosides, 3β,7β,25-trihydroxycucurbita-5,23(E)-dien-19-al (2), momordicine I (3), momordicine II (4), 3-hydroxycucurbita-5,24-dien-19-al-7,23-di-O-β-glucopyranoside (5), and kuguaglycoside G (6), were isolated from the whole plant of Momordica charantia. Their structures were determined by chemical and spectroscopic methods. Momordicoside X (1) was evaluated for insulin secretion activity in an in vitro insulin secretion assay and displayed moderate activity.

Key words

Momordica charantia - Cucurbitaceae - cucurbitane-type triterpenoid - momordicoside X

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Dr. Jun Ma

U. S. Food and Drug Administration
Center for Food Safety and Applied Nutrition

5100 Paint Branch Parkway

20740 College Park, Maryland

United States

Phone: + 1 30 14 36 17 77

Fax: + 1 30 14 36 30 77

Email: jun.ma@fda.hhs.gov

    www.thieme-connect.de/ejournals/toc/plantamedica