ABSTRACT
We present a patient with an initial and acute presentation of jaundice and marked persistent pruritus. Laboratory and radiology test results eliminated the possibility of acute hepatitis A/B/C viral infections, primary biliary cirrhosis, autoimmune hepatitis, Wilson disease, paraneoplastic cholestasis, and obstructive biliary disease. Centrilobular cholestasis was prominent in a liver biopsy specimen. Benign recurrent intrahepatic cholestasis (BRIC) was diagnosed through a review of the clinical history, available data, and the subsequent exclusion of other possible etiologies. The patient's clinical features resolved within 3 months of medical treatment.
KEYWORDS
Recurrent pruritus - jaundice - cholestasis
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Lawrence U LiuM.D.
Division of Liver Diseases, The Mount Sinai Medical Center
One Gustave L. Levy Place, Box 1104, New York, NY 10029
Email: Lawrence.Liu@mountsinai.org