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Semin Neurol 2010; 30(3): 273-286
DOI: 10.1055/s-0030-1255217
© Thieme Medical Publishers

Neurotoxicity of Cancer Chemotherapy

Edward J. Dropcho1
  • 1Department of Neurology, Indiana University Medical Center, Indianapolis, Indiana
Further Information

Publication History

Publication Date:
24 June 2010 (online)

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ABSTRACT

Neurologic dysfunction is a common side effect of many chemotherapy drugs. For several agents, neurotoxicity is common, severe, and can be dose-limiting. As the list of newer chemotherapy agents and systemic “targeted therapies” grows, so does the number and variety of potential neurotoxicities. This is a review of the clinical features of chemotherapy-induced syndromes involving the central and peripheral nervous systems.

KEYWORDS

Chemotherapy adverse effects - polyneuropathy

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Edward J DropchoM.D. 

Department of Neurology, Indiana University Medical Center

CL 292, Indianapolis, Indiana 46202

Email: edropcho@iupui.edu