Abstract
Achiral and chiral imidazoliophanes were prepared by N- alkylation of chiral imidazole derivatives
featuring an α-amino acid motif and subsequent double quarternization
of the imidazole N3-position of the corresponding precyclophanes.
Eight new optically pure imidazoliophanes were synthesized in good
yields, whereas the molecular structure of one achiral analogue
was confirmed by X-ray analysis.
Key words
cyclophanes - imidazoliophanes - amino acids - chiral pool - ligands
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18 CCDC 757647 contains the supplementary
crystallographic data for this paper. These data can be obtained
free of charge at www.ccdc.cam.ac.uk/conts/retrieving.html [or
from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge
CB2 1EZ, UK; fax: +44(1223)336033, E-mail: deposit@ccdc.cam.ac.uk].
