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Synlett 2010(13): 2045-2046
DOI: 10.1055/s-0030-1258508
DOI: 10.1055/s-0030-1258508
SPOTLIGHT
© Georg Thieme Verlag
Stuttgart ˙ New York
Bis(benzotriazolyl)methanethione
Further Information
Publication History
Publication Date:
28 July 2010 (online)
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Introduction
Bis(benzotriazolyl)methanethione, a reagent derived from benzotriazole, is a thiophosgene equivalent for thioacylations and for the synthesis of different thiocarbonyl compounds. [¹] [²] Compared to thiophosgene, bis- (benzotriazolyl)methanethione is found to be more advantageous due to its high stability and less toxicity. It is a crystalline solid, easy to handle, and it can be stored for years at room temperature. Bis(benzotriazolyl)methanethione can be obtained in high yield as yellow crystals (mp 170-171 ˚C) starting from benzotriazole (Scheme [¹] ). [³]
Scheme 1
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