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Synlett 2010(17): 2679-2680
DOI: 10.1055/s-0030-1258588
DOI: 10.1055/s-0030-1258588
SPOTLIGHT
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthetic Applications of Diethyl Ethoxymethylenemalonate
Further Information
Publication History
Publication Date:
30 September 2010 (online)
Introduction
Diethyl ethoxymethylenemalonate (EMME, Figure [¹] ), a liquid with a boiling point of 279-281 ˚C, is a very versatile reagent, extensively used for the synthesis of heterocyclic systems. The main application of this reagent is its use in the Gould-Jacobs reaction.
Figure 1 EMME
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