Severe Rhabdomyolysis Caused by Valproic Acid in a Neonate with Seizures and Chromosomal Abnormalities

Key words

valproic acid - rhabdomyolysis - neonate - chromosomal abnormalities

Schlüsselwörter

Valproinsäure - Rhabdomyolyse - Neugeborenes - chromosomale Veränderungen

References

• 1 Kottlors M, Jaksch M, Ketelsen UP. et al . Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency.  Neuromusc Disord. 2001;  11 757-759
• 2 Lheureux PE, Hantson P. Carnitine in the treatment of valproic acid-induced toxicity.  Clin Toxicol. 2009;  47 101-111
• 3 Meyer S, Kuhlmann MK, Peters FT. et al . Severe valproic acid intoxication is associated with atrial tachycardia: secondary detoxicaton by hemoperfusion.  Klin Padiatr. 2005;  217 82-85
• 4 Naranjo CA, Busto U, Sellers EM. et al . A method for estimating the probability of adverse drug reactions.  Clin Pharmacol Ther. 1981;  30 239-245
• 5 Prandstetter C, Tamesberger M, Wagner. et al . Medical prescriptions to premature and newborn infants in an Austrian neonatal intensive care unit.  Klin Padiatr. 2009;  221 312-317
• 6 Roth B. Off-label and unlicenced use of drugs in neonatal intensive care.  Klin Padiatr. 2009;  22 275-277

Correspondence