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Synthesis 2012(7): 1037-1042
DOI: 10.1055/s-0031-1289743
DOI: 10.1055/s-0031-1289743
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New YorkCopper(I)-Catalyzed, One-Pot Synthesis of Multisubstituted Indoles from 2-Iodoanilines and Ethyl Buta-2,3-dienoate
Further Information
Received
30 December 2011
Publication Date:
14 March 2012 (online)
Publication History
Publication Date:
14 March 2012 (online)

Abstract
Reactions of 2-iodoanilines with ethyl buta-2,3-dienoate catalyzed by potassium carbonate and CuI in one pot generate the corresponding ethyl 2-methyl-1H-indole-3-carboxylate products in moderate yields under mild conditions.
Key words
indoles - aniline - allenes - copper - catalysis
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