Di-tert-butyl Azodicarboxylate

Introduction

Di-tert-butyl azodicarboxylate (DBAD, 1, Figure [1]), also represented as BocN=NBoc, is a yellow crystalline reagent, insoluble in water. It is a light-sensitive compound with a melting point in the range of 90–92 °C.[ ¹ ]

Figure 1 Di-tert-butyl azodicarboxylate (DBAD)

DBAD (1) has been widely used for several important reactions and for the synthesis of natural and biological active compounds. Recently, several examples have been published showing the relevance of this reagent in key organic reactions, especially in the α-amination of carbonylic compounds.[ ² ] 

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