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Synthesis 2012; 44(13): 2079-2083
DOI: 10.1055/s-0031-1291161
paper
© Georg Thieme Verlag Stuttgart · New York

Montmorillonite K-10 Catalyzed, Microwave-Assisted Cyclization of Acetylenic Amines: An Efficient Synthesis of Pyrrolocoumarins and Pyrroloquinolones

K. C. Majumdar*
Department of Chemistry, University of Kalyani, Kalyani 741235, W. B., India, Fax: +91(33)25828282   eMail: kcm@klyuniv.ac.in
,
Sudipta Ponra
Department of Chemistry, University of Kalyani, Kalyani 741235, W. B., India, Fax: +91(33)25828282   eMail: kcm@klyuniv.ac.in
,
Tapas Ghosh
Department of Chemistry, University of Kalyani, Kalyani 741235, W. B., India, Fax: +91(33)25828282   eMail: kcm@klyuniv.ac.in
› Institutsangaben
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Publikationsverlauf

Received: 22. Februar 2012

Accepted after revision: 24. April 2012

Publikationsdatum:
31. Mai 2012 (online)

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Abstract

A microwave-assisted montmorillonite K-10 catalyzed synthesis of pyrrolocoumarins and pyrroloquinolones from acetylenic amine is described. The reaction utilizes montmorillonite K-10 as an inexpensive, recyclable, and environmentally benign acid catalyst. Reactions were completed in few minutes under microwave irradiation and provided excellent yields. The efficient and eco-friendly catalyst and the convenience of the product isolation make the process an attractive alternative for the synthesis of these important heterocycles.

Key words

microwave irradiation - montmorillonite K-10 - acety­lenic amine - pyrrolocoumarin - pyrroloquinolone

Supporting Information

    for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
  • Supporting Information
 

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