Development of Tartaric Acid Derived Hydrogen-Bond Donors

Markus Boris Lauber; Roland Fröhlich; Jan Paradies

doi:10.1055/s-0032-1316759

Synthesis, Inhaltsverzeichnis

Synthesis 2012; 44(20): 3209-3215
DOI: 10.1055/s-0032-1316759

paper

Development of Tartaric Acid Derived Hydrogen-Bond Donors

Markus Boris Lauber

^aInstitute for Organic Chemistry, Karlsruhe Institute of Technology, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany, Fax: +49(721)60848581 eMail: jan.paradies@kit.edu

,

Roland Fröhlich

^bInstitute of Organic Chemistry, University of Münster, Corrensstrasse 40, 48149 Münster, Germany

,

Jan Paradies*

^aInstitute for Organic Chemistry, Karlsruhe Institute of Technology, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany, Fax: +49(721)60848581 eMail: jan.paradies@kit.edu

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Abstract

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Abstract

A flexible synthesis of bifunctional thiourea derivatives based on the TADDOL framework is described. Hydroxy as well as primary, secondary, and tertiary amino-substituted bifunctional hydrogen-bond donors were synthesized.

Key words

TADDOL - thiourea - hydrogen bond - asymmetric synthesis - catalyst

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Referenzen

References

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