Recent Developments in Nitrone Chemistry: Some Novel Transformations

Jiong Yang

doi:10.1055/s-0032-1317096

Synlett, Inhaltsverzeichnis

Synlett 2012; 23(16): 2293-2297
DOI: 10.1055/s-0032-1317096

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Recent Developments in Nitrone Chemistry: Some Novel Transformations

Jiong Yang*

Department of Chemistry, Texas A&M University, College Station, Texas 77843-3255, USA, Fax: +1(979)8454719 eMail: yang@mail.chem.tamu.edu

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Abstract

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Abstract

Despite the long history of nitrone chemistry, novel transformations of nitrones continue to be discovered. This article describes some recent breakthroughs in the development of new transformations of nitrones. These new reactions include formal [3+3] cycloaddition of nitrones and vinylcarbenes to give 3,6-dihydro-1,2-oxazines, tandem cyclization–[3+3] cycloaddition of nitrones and enynones to give furo[3,4-d][1,2]oxazines, [2+2+3] cycloaddition of nitrones and 1,6-enynes to give tricyclic 1,2-oxazepanes, reaction of nitrones and 2-azido acrylates to form 1,2,4,5-tetrasubstituted imidazoles, and reactions of α,β-unsaturated N-aryl ketonitrones and activated alkynes to generate C3-quaternary indolenines.

Key words

nitrone - dipolar cycloaddition - tandem reaction - catalysis - indolenine

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Referenzen

References

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