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Synthesis 2012; 44(20): 3191-3196
DOI: 10.1055/s-0032-1317136
DOI: 10.1055/s-0032-1317136
paper
Catalyst-Free Amidation of Trimethylsilyl Ketene Imines with Isocyanates
Further Information
Publication History
Received: 03 July 2012
Accepted after revision: 27 July 2012
Publication Date:
21 August 2012 (online)
Abstract
A catalyst-free method for the amidation of N-trimethylsilyl ketene imines using isocyanates is reported. A working hypothesis on the reaction pathway includes silatropism from the ketene nitrogen to the isocyanate oxygen as the driving force of the process.
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References
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For reactions of silyl ketene imines with electrophiles, see: