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Synlett 2012; 23(18): 2667-2671
DOI: 10.1055/s-0032-1317344
DOI: 10.1055/s-0032-1317344
letter
An Efficient Method for Phosphorylation of Alcohols: Preparation of Porphyrin-Derived Phosphates
Weitere Informationen
Publikationsverlauf
Received: 26. Juli 2012
Accepted after revision: 10. September 2012
Publikationsdatum:
09. Oktober 2012 (online)
Abstract
An effective method for the phosphorylation of phenols and various alcohols including porphyrins bearing hydroxyl groups was developed. The reaction of 6,7-bis(3-hydroxypropyl)-1,3,5,8-tetramethyl-2,4-divinylporphyrin with dialkyl chlorophosphate in the presence of DABCO as both a catalyst and a proton scavenger gave the desired phosphate in 97% yield.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information
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