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DOI: 10.1055/s-0032-1317353
PEG 400
Publication History
Publication Date:
01 October 2012 (online)
Introduction
Polyethylene glycol 400 (PEG 400) is a water-soluble and hygroscopic polymer with a molecular weight of 400 Da.[ 1 ] At room temperature it exists as colorless viscous liquid. Reactions promoted by PEG 400 have attracted attention due to their ease of workup and inexpensive and eco-friendly nature. It can also act as phase-transfer catalyst.
Till date reactions involving PEG 400 have been carried out and investigated, for example, Heck reaction,[ 2 ] Lindlar catalytic hydrogenation,[ 3 ] asymmetric dihydroxylation,[ 4 ] Baylis–Hillman reaction,[ 5 ] Biginelli reaction,[ 6 ] Suzuki–Miyaura coupling,[ 7 ] Stille cross-coupling,[ 8 ] Wacker reaction,[ 9 ] asymmetric aldol reaction,[ 10 ] 3,4-dihydropyrimidones via Biginelli reaction,[ 11 ] Strecker reaction,[ 12 ] etc.
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References
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