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Synlett 2012; 23(20): 2927-2930
DOI: 10.1055/s-0032-1317671
letter
© Georg Thieme Verlag Stuttgart · New York

Click Synthesis of 5-Substituted 1H-Tetrazoles from Aldehydes, Hydroxyl­amine, and [bmim]N3 via One-Pot, Three-Component Reaction

Majid M. Heravi*
a   Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran   Fax: +98(21)88041344   eMail: mmh1331@yahoo.com
,
Azadeh Fazeli
a   Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran   Fax: +98(21)88041344   eMail: mmh1331@yahoo.com
,
Hossein A. Oskooie
a   Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran   Fax: +98(21)88041344   eMail: mmh1331@yahoo.com
,
Yahya S. Beheshtiha
a   Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran   Fax: +98(21)88041344   eMail: mmh1331@yahoo.com
,
Hassan Valizadeh
b   Department of Chemistry, Faculty of Sciences, Azarbaijan University of Tarbiat Moallem, Tabriz, Iran
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Publikationsverlauf

Received: 13. Oktober 2012

Accepted after revision: 29. Oktober 2012

Publikationsdatum:
23. November 2012 (online)

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Abstract

An easy and efficient one-pot, three-component method for the synthesis of 5-substituted 1H-tetrazole derivatives, via the reaction of aldehydes, hydroxylamine, and [bmim]N3, is reported.

Key words

5-substituted 1H-tetrazoles - three-component - click reaction - cyclization - aldehydes - 1-butyl-3-methylimidazolium azide
 

  • References and Notes

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