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Synthesis 2013; 45(1): 111-117
DOI: 10.1055/s-0032-1317781
DOI: 10.1055/s-0032-1317781
paper
A One-Pot Transition-Metal-Free Tandem Process to 1,4-Benzodiazepine Scaffolds
Weitere Informationen
Publikationsverlauf
Received: 31. August 2012
Accepted after revision: 16. November 2012
Publikationsdatum:
30. November 2012 (online)
Abstract
An efficient and practical method for the synthesis of 1,4-benzodiazepines is reported. This methodology offers a transition-metal-free tandem process in one pot. This process is applicable to the construction of a wide variety of 1,4-benzodiazepines and other tricyclic systems with high potential biological and pharmacological activities.
Key words
1,4-benzodiazepines - pyridazinobenzodiazepines - one-pot reaction - transition-metal-free tandem processSupporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
-
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