Mechanistic Insights into Palladium Leaching in Novel Pd/C-Catalyzed 
Boron-Heck Reaction of Arylboronic Acid

Mahesh G. Dighe; Sachin L. Lonkar; Mariam S. Degani

doi:10.1055/s-0032-1318110

Synlett, Table of Contents

Synlett 2013; 24(3): 347-350
DOI: 10.1055/s-0032-1318110

letter

Mechanistic Insights into Palladium Leaching in Novel Pd/C-Catalyzed Boron-Heck Reaction of Arylboronic Acid

Mahesh G. Dighe

Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga (E), Mumbai 400019, India Fax: +91(22)33611020 Email: ms.degani@ictmumbai.edu.in

,

Sachin L. Lonkar

Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga (E), Mumbai 400019, India Fax: +91(22)33611020 Email: ms.degani@ictmumbai.edu.in

,

Mariam S. Degani*

Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga (E), Mumbai 400019, India Fax: +91(22)33611020 Email: ms.degani@ictmumbai.edu.in

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Abstract

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Abstract

For the first time, Pd/C has been used for the Boron-Heck reaction, and the detailed mechanistic aspects of the reaction have been proven experimentally by a leaching test as well as by cyclic voltammetry studies. The results indicate that palladium leaching as a Pd(II) species, by oxidative addition of the arylboronic acid, is responsible for the reaction.

Key words

heterogeneous catalysis - Pd/C - arylboronic acids - palladium leaching - Boron-Heck reaction

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References

References and Notes
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