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Synthesis 2013; 45(13): 1837-1842
DOI: 10.1055/s-0033-1338863
DOI: 10.1055/s-0033-1338863
paper
Borylation of Arenes with Bis(hexylene glycolato)diboron
Further Information
Publication History
Received: 06 May 2013
Accepted: 07 May 2013
Publication Date:
23 May 2013 (online)
This paper is dedicated to Professor Scott Denmark on the occasion of his 60th birthday.
Abstract
A series of diolate-substituted diboron compounds were investigated as reagents for iridium-catalyzed C–H borylations of arenes. These studies showed that commercially available bis(hexylene glycolato)diboron reacts with arenes in the presence of the catalyst generated from [Ir(COD)OMe]2 and di-tert-butylbipyridine. This reagent is prepared from a less expensive diol than the more commonly used bis(pinacolato)diboron reagent.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
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