Recent Developments in the Application of Organocatalysis to Glycosylations

Edward I. Balmond; M. Carmen Galan; Eoghan M. McGarrigle

doi:10.1055/s-0033-1338970

Synlett, Table of Contents

Synlett 2013; 24(18): 2335-2339
DOI: 10.1055/s-0033-1338970

synpacts

Recent Developments in the Application of Organocatalysis to Glycosylations

Edward I. Balmond

^aSchool of Chemistry, University of Bristol, Cantock’s Close, Bristol, BS8 1TS, UK Email: M.C.Galan@bristol.ac.uk

,

M. Carmen Galan*

^aSchool of Chemistry, University of Bristol, Cantock’s Close, Bristol, BS8 1TS, UK Email: M.C.Galan@bristol.ac.uk

,

Eoghan M. McGarrigle*

^bCentre for Synthesis and Chemical Biology, UCD School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland Fax: +353(1)7161178 Email: Eoghan.McGarrigle@ucd.ie

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Abstract

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Abstract

The regioselective and stereoselective synthesis of glycosidic bonds still remains one of the most challenging areas within organic synthesis. Despite the broad use of organocatalysis within asymmetric synthesis, its application towards oligosaccharide synthesis is still in its infancy. This article highlights some recent examples of organocatalysts being used for regio- and stereoselective glycosylations and looks towards the future of the area.

Key words

glycosylation - catalysis - organocatalysis - stereoselective synthesis - carbohydrates - regioselective synthesis

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References

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