p-Toluenesulfonic Acid Catalyzed One-Pot Synthesis of 4H-Pyrido[1,2-a]pyrimidin-4-one Derivatives

Abstract

A novel one-pot protocol has been developed for the construction of alkenylated 4H-pyrido[1,2-a]pyrimidin-4-one derivatives from 2-aminopyridine in the presence of PTSA. The present approach opens a new way for the formation of C–C and C–N bonds under mild conditions.

Key words

metal-free - 4H-pyrido[1,2-a]pyrimidin-4-ones - PTSA - 2-aminopyridine - multicomponent reactions

• References and Notes

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