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Synlett 2013; 24(16): 2153-2159
DOI: 10.1055/s-0033-1339516
DOI: 10.1055/s-0033-1339516
letter
Palladium(II)-Catalyzed Oxidative ortho-Arylation of 2-Phenylpyridines
Further Information
Publication History
Received: 21 May 2013
Accepted after revision: 11 July 2013
Publication Date:
21 August 2013 (online)
Abstract
A palladium(II)-catalyzed oxidative ortho-arylation of 2-phenylpyridines via direct C–H activation with aryl boric acids is described. The reaction could be conducted under mild conditions in the presence of Pd(OAc)2/Cu(OTf)2/TBHP system, and a variety of the azacyclic compounds bearing a biaryl unit were obtained with moderate to good yields.
Key words
palladium - C–H functionalization - ortho arylation - 2-phenylpyridines - arylboronic acidSupporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information
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