Small-Cell Lung Carcinoma Presenting as Paraneoplastic Autoimmune Optic Neuritis with
                    Retinitis

Klin Monbl Augenheilkd 2014; 231(4): 453-454
DOI: 10.1055/s-0034-1368285

Der interessante Fall

Georg Thieme Verlag KG Stuttgart · New York

Kleinzelliges Lungenkarzinom präsentiert sich als paraneoplastische autoimmune optische Neuritis mit Retinitis

O. Passarin

¹Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland (Chairman: Prof F. Behar-Cohen)

,

S. Reymond

²Department of Neurology, Hôpital du Valais Sion, Switzerland (Chairman: Prof J. A. Ghika)

,

A. Michel

³Ophtalmologue FMH, Avenue du Rothorn 11, 3960 Sierre, Switzerland

,

J.-A. Ghika

²Department of Neurology, Hôpital du Valais Sion, Switzerland (Chairman: Prof J. A. Ghika)

,

Y. Guex-Crosier

¹Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland (Chairman: Prof F. Behar-Cohen)

References
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2 Cross SA, Salomao DR, Parisi JE et al. Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG. Ann Neurol 2003; 54: 38-50
3 Damek DM. Paraneoplastic retinopathy/optic neuropathy. Curr Treat Options Neurol 2005; 7: 57-67
4 Shiraga S, Adamus G. Mechanism of CAR syndrome: anti-recoverin antibodies are the inducers of retinal cell apoptotic death via the caspase 9- and caspase 3-dependent pathway. J Neuroimmunol 2002; 132: 72-82
5 Murphy MA, Thirkill CE, Hart jr. WM. Paraneoplastic retinopathy: a novel autoantibody reaction associated with small-cell lung carcinoma. J Neuroophthalmol 1997; 17: 77-83